On the Thermodynamic Stability of Monoclinic Selenium

Franz, Philipp; Gobrecht, H.; Scheiba, M.; Wobig, D.; Kunze, Wolfgang

doi:10.1524/zpch.1978.111.2.163

Cited by 4 publications

(1 citation statement)

References 13 publications

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“…The calculation of Gibbs functions shall be outlined in some detail [7,8]. A substance consisting of two crystal modifications designated as a and/3, respectively, is assumed.…”

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confidence: 99%

Applied chemical thermodynamics and kinetics on pharmaceutical compounds

Marti

1988

Journal of Thermal Analysis

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The important role of thermoanalytical methods in the field of pharmaceutical and galenic research is outlined. The thermodynamic stability of polymorphic forms of a substance is discussed.The development of a pharmaceutical compound or a dosage form is a long-range task affording normally a period of more than ten years. Many research and development steps are necessary from the first step the synthesis of a pharmaceutical compound for which a certain therapeutic effect can be expected to the final step of the galenic formulation.A second development pathway gains to-day a marked importance in creating new dosage forms for already known pharmaceutical compounds. The whole field of the galenic development changed in the last years to a major research and development task. Of course the question may be put foreward what are the rational facts causing such a shift of emphasis. First of all many John Wiley & Sons, Limited, Chichester Akaddmiai Kiad6, Budapest

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“…The calculation of Gibbs functions shall be outlined in some detail [7,8]. A substance consisting of two crystal modifications designated as a and/3, respectively, is assumed.…”

mentioning

confidence: 99%