A new approach to the relativistic treatment of the fermion-boson system, based on the extension of the SL(2, C) groupTheoretical Physics Department Dniepropetrovsk National University 72 Gagarina av., Dniepropetrovsk 49050, Ukraine Abstract A new technique for constructing the relativistic wave equation for the two-body system composed of the spin-1/2 and spin-0 particles is proposed. The method is based on the extension of the SL(2, C) group to the Sp(4, C) one. The obtained equation includes the interaction potentials, having both the Lorentz-vector and Lorentz-tensor structure, exactly describes the relativistic kinematics and possesses the correct one-particle limits. The comparison with results of other approaches to this problem is discussed.