A rational Diophantine m-tuple is a set of m nonzero rationals such that the product of any two of them increased by 1 is a perfect square. The first rational Diophantine quadruple was found by Diophantus, while Euler proved that there are infinitely many rational Diophantine quintuples. In 1999, Gibbs found the first example of a rational Diophantine sextuple. In this paper, we prove that there exist infinitely many rational Diophantine sextuples. set 1 16 , 33 16 , 17 4 , 105 16 found by Diophantus (see [4]). Euler found infinitely many rational Diophantine quintuples (see [20]), e.g. he was able to extend the integer Diophantine quadruple {1, 3, 8, 120} found by Fermat, to the rational quintuple 1, 3, 8, 120, 777480 8288641 . Let us note that Baker and Davenport [2] proved that Fermat's set cannot be extended to an integer Diophantine quintuple, while Dujella and Pethő [15] showed that there is no integer Diophantine quintuple which contains the pair {1, 3}. For results on the existence of infinitely many rational D(q)-quintuples, i.e. sets in which xy + q is always a square, for q = 1 see [12].