The Quality of Service (QoS) support for multimedia multiuser sessions is essential to the success of fourth generation mobile networks. However, it requires the QoS control for those sessions independently of the movement of users, QoS model, and link capacity supported by wired and wireless networks in the end-toend session path. This paper presents the Multiuser Session Control (MUSC) mechanism to provide QoS mapping and QoS adaptation of multiuser sessions over heterogeneous and mobile networks. The coordination of the QoS mapping and QoS adaptation controllers allows the adaptation of the session to the current network conditions and the dynamic selection of the most suitable network service class to map the session. The MUSC control is based on the session requirements, existing services class and their available bandwidth. Performance evaluation shows the impact of the MUSC proposal by analysing its convergence time, as well as the one-way delay and throughput of multiuser sessions in a QoS-aware mobile scenario.