The key derivation function is a specific cryptographic algorithm that transforms private string and public strings into one or more cryptographic keys. The cryptographic keys are essential for protecting electronic data during transmission on the internet. This function is designed based on a computational extractor and pseudorandom expander and is typically constructed using various cryptography ciphers such as stream ciphers, keyed-hash message authentication codes, and block ciphers. Having secure and efficient key derivation function designs is essential in the development of numerous security systems. A vulnerable key derivation function could potentially give attackers the ability to compromise an otherwise secure cryptosystem. This research proposes a different approach by combining two different cryptography ciphers to develop key derivation functions. The findings demonstrate that a computational extractor utilizing keyed-hash message authentication codes and a pseudorandom expander using stream ciphers maintain the highest level of security while also providing efficiency benefits in terms of execution time compared to existing key derivation function schemes.