In this research, we obtain the sufficient conditions that guarantee that the set of solutions for an impulsive fractional differential inclusion involving a w-weighted ψ-Hilfer fractional derivative, D0,tσ,v,ψ,w,of order μ∈(1,2), in infinite dimensional Banach spaces that are not empty and compact. We demonstrate the exact relation between a differential equation involving D0,tσ,v,ψ,w of order μ ∈(1,2) in the presence of non-instantaneous impulses and its corresponding fractional integral equation. Then, we derive the formula for the solution for the considered problem. The desired results are achieved using the properties of the w-weighted ψ-Hilfer fractional derivative and appropriate fixed-point theorems for multivalued functions. Since the operator D0,tσ,v,ψ,w includes many types of well-known fractional differential operators, our results generalize several results recently published in the literature. We give an example that illustrates and supports our theoretical results.