Once-only flexible sigmoidoscopy screening in prevention of colorectal cancer: a multicentre randomised controlled trial

S3-Leitlinie – Kolorektales Karzinom

“…In einer randomisierten Studie aus England wurde im Vergleich zu keinem Screening durch eine einmalige Sigmoidoskopie nach einer Nachbeobachtungszeit von 11,2 Jahren eine Senkung der KRK-bedingten Mortalität um 43 % und eine Senkung der Inzidenz kolorektaler Karzinome um 33 %, die distaler Karzinome um 50 % beobachtet [122].…”

Red and processed meat intake and risk of colorectal adenomas: a systematic review and meta-analysis of epidemiological studies

“…The histologic type, size and number of adenomas determine the risk of developing colorectal cancer (3). Screening for colorectal adenomas and removal of such adenomas by colonoscopy is an important strategy to reduce colorectal cancer risk (4). Although lifestyle factors are considered to be of major importance in colorectal cancer etiology (5)(6)(7)(8)(9), less is known about how such factors are related to risk of colorectal adenomas.…”

Efficacy of an educational intervention on family physicians’ risk assessment and management of colorectal cancer

“…Screening for CRC has been shown to decrease CRC mortality for average risk as well as high-risk individuals (Atkin et al 2010;Hardcastle et al 1996;Hewitson et al 2008;Kronborg et al 1996;Mandel et al 1993;Schoen et al 2012). The American College of Physicians (ACP) recommends that clinicians assess risk for CRC in all adults, and that average-risk individuals screen for CRC using fecal occult blood testing (FOBT) annually, flexible sigmoidoscopy every 5 years, or optical colonoscopy every 10 years, beginning at age 50 and continuing until age 75 (Qaseem et al 2012).…”