Oncocytic papillary cystadenoma of the larynx: a case report

Oncocytic papillary cystadenoma of right laryngeal ventricle

“…OPC does not appear to be precursory to malignancy [1,5]. Several cases of concurrent OPC and laryngeal carcinoma have been described, but the two conditions are believed to have arisen independently, most likely due to common risk factors [4][5][6].…”

Unilateral Tubarial Oncocytic Papillary Cystadenoma Presenting with Epistaxis

“…Minor salivary gland tumors (MSGTs) account for <20% of all salivary gland tumors, and only 2-3% of all head and neck neoplasms 6 , 9 , 11 .They are usually found in individuals aged 50-60 years with a slight female predominance 3 , 11 . In contrast to major salivary gland tumors where malignancy is unlikely, those arising from minor salivary glands are likely malignant with either adenoid cystic carcinoma or mucoepidermoid carcinoma as the most common 9 , 11 .…”

“…According to the World Health Organization histological classification of salivary gland tumors, OPC is a cystic lesion lined by oncocytic epithelium with occasional luminal papillary projections. They are mostly reported among those aged 70-80 years and strongly associated with smokers or tobacco users 6 , 7 . It mostly presents as a single cyst and rarely in a more diffuse pattern as multicysts 6 .…”

“…They are mostly reported among those aged 70-80 years and strongly associated with smokers or tobacco users 6 , 7 . It mostly presents as a single cyst and rarely in a more diffuse pattern as multicysts 6 . In 2020, Hwang et al 8 reported a case of oncocytic cysts of bilateral tori tubarii.…”

“…A sudden onset of recurrent epistaxis in adult men/older men without any history of using such drugs or a recent facial trauma is also the common presentation or warning sign for sinonasal diseases, particularly for malignant tumors, such as squamous cell carcinoma, minor salivary gland carcinoma, nasopharyngeal carcinoma, and lymphoma. Oncocytic papillary cystadenoma (OPC) is a very rare benign tumor commonly found in the salivary glands, mainly reported in minor salivary glands, and usually is observed in individuals aged 60-70 years 3 , 4 , 5 , 6 . A few cases reported were seen within the intraoral minor salivary glands and parotid glands, which all presented with a painless mass, whereas some cases were detected within the larynx, mainly at the supraglottic structures, and an increasing tumor size causes hoarseness, dysphonia, or rarely airway obstruction 7 .…”