2015
DOI: 10.1016/j.acthis.2015.02.012
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Oncofetal expression of Wilms’ tumor 1 (WT1) protein in human fetal, adult and neoplastic skeletal muscle tissues

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Cited by 23 publications
(28 citation statements)
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“…These latter antibodies give rise to a diffuse and strong cytoplasmic expression in rhabdomyosarcomas, regardless the subtypes (embryonal and alveolar) and the age of patients (Carpentieri et al, 2002;Sebire et al, 2005;Salvatorelli et al, 2011Salvatorelli et al, , 2015Bisceglia et al, 2011a,b;Magro et al, 2015b;Parenti et al, 2015). This unexpected finding is explained by the detection of WT1 in the cytoplasm of human developing skeletal muscle tissues (Parenti et al, 2013;Magro et al, 2015b;Musumeci et al, 2015). Although a similar cytoplasmic WT1 expression has been found in DSRCT, the staining intensity is usually weak (Barnoud et al, 2000;Salvatorelli et al, 2015).…”
Section: Desmoplastic Small Round Cell Tumor (Dsrct)mentioning
confidence: 58%
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“…These latter antibodies give rise to a diffuse and strong cytoplasmic expression in rhabdomyosarcomas, regardless the subtypes (embryonal and alveolar) and the age of patients (Carpentieri et al, 2002;Sebire et al, 2005;Salvatorelli et al, 2011Salvatorelli et al, , 2015Bisceglia et al, 2011a,b;Magro et al, 2015b;Parenti et al, 2015). This unexpected finding is explained by the detection of WT1 in the cytoplasm of human developing skeletal muscle tissues (Parenti et al, 2013;Magro et al, 2015b;Musumeci et al, 2015). Although a similar cytoplasmic WT1 expression has been found in DSRCT, the staining intensity is usually weak (Barnoud et al, 2000;Salvatorelli et al, 2015).…”
Section: Desmoplastic Small Round Cell Tumor (Dsrct)mentioning
confidence: 58%
“…Notably, some cases of embryonal rhabdomyosarcomas may lack myogenin expression (Dias et al, 2000;Parham et al, 2012), so it is wise to include in the immunohistochemical panel also antibodies against both the Cand N-terminus of WT1 protein (clone WT 6F-H2). These latter antibodies give rise to a diffuse and strong cytoplasmic expression in rhabdomyosarcomas, regardless the subtypes (embryonal and alveolar) and the age of patients (Carpentieri et al, 2002;Sebire et al, 2005;Salvatorelli et al, 2011Salvatorelli et al, , 2015Bisceglia et al, 2011a,b;Magro et al, 2015b;Parenti et al, 2015). This unexpected finding is explained by the detection of WT1 in the cytoplasm of human developing skeletal muscle tissues (Parenti et al, 2013;Magro et al, 2015b;Musumeci et al, 2015).…”
Section: Desmoplastic Small Round Cell Tumor (Dsrct)mentioning
confidence: 64%
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