Oncology

Mayer, Jörg; Moore, Antony S.

doi:10.1016/b978-0-323-48253-0.00078-7

Cited by 3 publications

(2 citation statements)

References 10 publications

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“…Due to a wide range of different diagnoses of swelling on reptiles´ bodies biopsy is useful for externally palpable masses [21]. The best method for determining the diagnosis of neoplastic disease is tissue biopsy [1,21]. Reavill (2004) suggests fi neneedle aspiration biopsy of the affected area [26].…”

Section: Discussionmentioning

confidence: 99%

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Metastatic Cholangiocarcinoma in a Bearded Dragon (Pogona vitticeps)

et al. 2020

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AbstractA 6.5-year-old female bearded dragon (Pogona vitticeps) was presented with a swollen right pelvic limb. A tissue core biopsy from the swollen area was performed and a presumptive histopathological diagnosis of adenocarcinoma was made. This diagnosis was confirmed after limb amputation. Two months after amputation a sudden deterioration in the overall health of the patient occurred. Ultrasound examination of the coelomic cavity revealed hypoechoic lesions in the liver. The patient was euthanized and submitted for necropsy which revealed a severely enlarged liver with multiple coalescing yellowish nodules. Cholangiocarcinoma of the liver with metastases to the spleen, left mesovarium and right pelvic limb was diagnosed after histopathological examination.

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Section: Discussionmentioning

confidence: 99%

“…The fi nding of a mass on a reptile´s body does not immediately mean that the lesion is neoplastic. The appropriate management of the swelling without histological or cytological confi rmation is not possible [21]. Therefore, it is very useful to biopsy such lesions and perform further examinations.…”

Section: Introductionmentioning

confidence: 99%

Metastatic Cholangiocarcinoma in a Bearded Dragon (Pogona vitticeps)

et al. 2020

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Malignant ovarian dysgerminoma in a 16-year-old leopard gecko (Eublepharis macularius)

Zborilova¹,

Dietz²,

Heckers³

et al. 2023

Vet. Med.

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The 16-year-old female leopard gecko (Eublepharis macularius) was presented with distended coelom and cachexia. Examination of the faecal sample ruled out the presence of protozoan parasites. A radiographic examination confirmed the presence of radiopaque foreign material in the intestine. The conservative treatment with tramadol, butylscopolamine, famotidine, vitamin B complex, and supportive fluid therapy with Hartmann solution and Duphalyte, was performed for 14 days. Ultrasonographic examination revealed the presence of a large mass adherent to the liver (with hypoechoic regions), a thin-walled cystic structure close to the liver, and coelomic effusion. Surgical exploration revealed a large mass on the right ovary. The unilateral (right) ovariectomy was performed. Histologic examination of the mass revealed dysgerminoma with an invasion of the ovarian bursa and blood vessels. Nine months after the surgery the patient was active and doing well. In reptiles, dysgerminoma is an uncommon type of neoplasia. To the best of our knowledge, this is the first case of dysgerminoma tumour diagnosed intravitally and treated successfully in lizards.

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Ileocolic Intussusception Associated with a Multicentric Round Cell Tumor in a Red-Tailed Boa (Boa constrictor constrictor)

Máté¹,

Simard

Ducatelle

et al. 2022

Journal of Herpetological Medicine and Surgery

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A 5-year-old, female red-tailed boa constrictor ( Boa constrictor constrictor ) was presented with hyporexia, regurgitation and progressive focal distention of the caudal coelom since two months. During physical examination a firm, well-demarcated and movable intracoelomic mass was detected halfway down the caudal coelom but no other abnormalities were noticed. Ultrasonographic examination showed the mass to consist of an intestinal intussusception. A complete blood cell count and serum biochemistry blood test results revealed mild anemia and leukocytosis as well as hyperuricemia and hyperphosphatemia with inversion of the calcium/phospohorus ratio. Explorative coeliotomy was performed and revealed anterograde invagination of the ileum into the colon through the ileocolic junction. Although the intussusception was surgically repositioned, the snake died three weeks post-operatively despite showing a good general condition and defecation following assisted feeding. During necropsy, a thickened wall of the caudal segment of the ileum that was previously involved in the intussusception was observed as well as the presence of multifocal, white nodules throughout the parenchyma of the liver, spleen and kidneys. Histopathological examination demonstrated a malignant round cell tumor of the ileum with infiltration of neoplastic round cells in the liver, spleen and kidneys. Immunohistochemical staining (CD3, CD20, MAC387, S100 and NSE) could not confirm the cell origin of the round cell tumor. The present case highlights the need to include round cell tumors as a differential diagnosis in the development of ileocolic intussusception in red-tailed boa constrictors.

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Oncology

Cited by 3 publications

References 10 publications

Metastatic Cholangiocarcinoma in a Bearded Dragon (Pogona vitticeps)

Metastatic Cholangiocarcinoma in a Bearded Dragon (Pogona vitticeps)

Malignant ovarian dysgerminoma in a 16-year-old leopard gecko (Eublepharis macularius)

Ileocolic Intussusception Associated with a Multicentric Round Cell Tumor in a Red-Tailed Boa (Boa constrictor constrictor)

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