A quantum memory or information processing device is subject to disturbance from its surrounding environment or inevitable leakage due to its contact with other systems. To tackle these problems, several control protocols have been proposed for quantum memory or storage. Among them, the fast-signal control or dynamical decoupling based on external pulse sequences provides a prevailing strategy aimed at suppressing decoherence and preventing the target systems from the leakage or diffusion process. In this paper, we review the applications of this protocol in protecting quantum memory under the non-Markovian dissipative noise and maintaining systems on finite speed adiabatic passages without leakage therefrom. We analyze leakage and control perturbative and nonperturbative dynamical equations including second-order master equation, quantum-state-diffusion equation, and one-component master equation derived from Feshbach PQ-partitioning technique. It turns out that the quality of fast-modulated signal control is insensitive to configurations of the applied pulse sequences. Specifically, decoherence and leakage will be greatly suppressed as long as the control sequence is able to effectively shift the system beyond the bath cutoff frequency, almost independent of the details of the control sequences which could be ideal pulses, regular rectangular pulses, random pulses and even noisy pulses.