One-dimensional copper(II) coordination polymers bridged both by μ-trans-oxamidates and phenyldicarboxylates: Synthesis, crystal structure and DNA binding studies

Li, Yan‐Tuan; Liu, Zhiqiang; Wu, Zhi‐Yong

doi:10.1016/j.jinorgbio.2008.05.011

Cited by 21 publications

(8 citation statements)

References 49 publications

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“…Obviously, these spectral characteristics reveal that the polymeric copper(II) complex interacts with HS-DNA through the intercalation mode that involves p-p stacking interaction between the aromatic chromophore and the base pairs of the DNA. These spectral changes are analogous to that of our previously reported a one-dimensional copper(II) polymer with formula of [Cu 2 (H 2 O) 2 (dmapox)(tpa) 2 ] n [50], whose interaction mode with DNA is intercalative binding. These observations for the polymeric copper(II) complex can be rationalized by the following reasons.…”

Section: Electronic Absorption Titrationsupporting

confidence: 87%

“…However, the molar conductivity in solution suggests that the polymeric copper(II) complex is intact as the whole, neutral polymer entity [Cu 2 (heae)(tpa)] n . This viewpoint is further evidenced by some 1D copper(II) coordination polymers with similar polymeric characteristics [36]. …”

Section: Synthetic Route and General Properties Of The Polymermentioning

confidence: 81%

“…The benzene dicarboxylate dianions, due to their versatile bonding modes with metal ions and their peculiar structures, involving carboxylate groups that are non-coplanar with themselves and with the benzene ring, could be good candidates for the preparation of polymeric MOFs [23,[33][34][35]. So far, many of new metal-polymers with interesting structures based on the bridging N,N 0 -bis(substituent)oxamides have been synthesized and their properties have been studied extensively [36,37]. However, the structures of reported those polymeric MOFs involving coordinating hydroxy groups in the N,N 0 -bis(substituent)oxamide bridging ligand appear to be rare.…”

Section: Synthetic Route and General Properties Of The Polymermentioning

confidence: 99%

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Synthesis, Structure, Cytotoxic Activities and DNA-Binding Properties of a 1D Copper(II) Complex Bridged both by Oxamidate and Terephthalato Groups

Jiang

et al. 2012

J Inorg Organomet Polym

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A new one-dimensional copper(II) polymer with formula of [Cu 2 (heae)(tpa)] n ÁnH 2 O, where heae 2-and tpa 2-stand for the dianions of N,N 0 -bis(N-hydroxyethylaminoethyl)oxamide and terephthalic acid, respectively, has been synthesized and characterized by elemental analysis, conductivity measurement, IR and electronic spectral studies, and single-crystal X-ray diffraction. The crystal structure consists of a one-dimensional copper(II) coordination polymeric chain constructed by the [Cu 2 (heae)] 2? cations as the inorganic second building units (SBUs) and the tpa 2-anions as linkers. The CuÁÁÁCu separations through the bridges of heae 2-and tpa 2-are 5.2472(6) and 10.9677(8) Å , respectively. Both the copper(II) ions have square pyramidal coordination geometries. A three-dimensional hydrogen bonding network is observed in the crystal. The measured molar conductivity suggests that the polymer may stay intact in solution as the 1D polymer in the crystal. The cytotoxicities of the polymeric copper(II) complex were tested by Sulforhodamine B (SRB) assays against human hepatocellular carcinoma cell SMMC-7721 and human lung adenocarcinoma cell A549. The polymer exhibits potent cytotoxic effects against the two cell lines. The binding properties of the copper(II) polymer with herring sperm DNA (HS-DNA) have been investigated by using UV absorption and fluorescence spectra and electrochemical techniques and viscosity. The results show that the copper(II) polymer interacts with HS-DNA in the mode of intercalation with the intrinsic binding constant of 1.07 9 10 4 M -1 .

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Section: Electronic Absorption Titrationsupporting

confidence: 87%

Section: Synthetic Route and General Properties Of The Polymermentioning

confidence: 81%

Section: Synthetic Route and General Properties Of The Polymermentioning

confidence: 99%

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Synthesis, Structure, Cytotoxic Activities and DNA-Binding Properties of a 1D Copper(II) Complex Bridged both by Oxamidate and Terephthalato Groups

Jiang

et al. 2012

J Inorg Organomet Polym

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“…The D value of 245 cm À1 agrees with monodentate carboxylate [4,40]. In addition, in 2, the broad absorption band at 3461 cm À1 and sharp band at 3622 cm À1 are assigned for (O-H) of coordinated and lattice water [27,40].…”

Section: Ir and Uv-vis Investigationmentioning

confidence: 55%

“…The plane of dm4bt is perpendicular to the aromatic rings of tpht. Usual for such compounds [4,11,40], Cu-O tpht distances (table 3) are significantly shorter than Cu-N thizo groups; this could be a consequence of the very short and strong Cu-O bond that increases the O-C bond order toward double bond character. In addition, copper formed monodentate and short bridges via one carboxylate.…”

Section: Description Of the Molecular Structure Of 1 Andmentioning

confidence: 99%

Synthesis, characterization, and crystal structure determination of two copper(II) complexes: [Cu(dm4bt)Cl₂(DMSO)] and [{Cu(dm4bt)(H₂O)(tpht)} · H₂O]_n

Al-Hashemi

Safari

Amani

et al. 2010

Journal of Coordination Chemistry

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Copper complexes, [Cu(dm4bt)Cl 2 (DMSO)] (1) and [{Cu(dm4bt)(H 2 O)(tpht)} Á H 2 O] n (2) (dm4bt, 2,2 0 -dimethyl-4,4 0 -bithiazole; tpht, terephthalate), have been synthesized and their crystal structures were determined by X-ray crystallography. Complex 1 was prepared from a reaction of CuCl 2 Á 2H 2 O with dm4bt and terephthalic acid in a mixture of methanol, water, and DMSO. Complex 2 was prepared from a reaction of CuCl 2 Á 2H 2 O with dm4bt, terephthalic acid, and ethylene diamine in a mixture of methanol and water. The two complexes were characterized by IR, UV-Vis spectroscopy, and single-crystal structure. Complex 2 was also characterized by electron paramagnetic resonance spectra. Complex 1 is a monomer while 2 is a coordination polymer. This copper tpht polymer has a cis-configuration of tpht rings opposed to zigzag chains with anti-configuration usually reported in the literature.

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Synthesis and Structure of a New Copper(II) Coordination Polymer Alternately Bridged by Oxamido and Carboxylate Groups: Evaluation of DNA/BSA Binding and Cytotoxic Activities

Jin

Zheng

et al. 2015

J Biochem & Molecular Tox

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A new one-dimensional (1D) copper(II) coordination polymer {[Cu2 (dmaepox)(dabt)](NO3) · 0.5 H2 O}n , where H3 dmaepox and dabt denote N-benzoato-N'-(3-methylaminopropyl)oxamide and 2,2'-diamino-4,4'-bithiazole, respectively, was synthesized and characterized by single-crystal X-ray diffraction and other methods. The crystal structure analysis revealed that the two copper(II) ions are bridged alternately by cis-oxamido and carboxylato groups to form a 1-D coordination polymer with the corresponding Cu · · · Cu separations of 5.1946(19) and 5.038(2) Å. There is a three-dimensional supramolecular structure constructed by hydrogen bonding and π-π stacking interactions in the crystal. The reactivity towards herring sperm DNA (HS-DNA) and bovine serum albumin (BSA) indicated that the copper(II) polymer can interact with the DNA in the mode of intercalation, and bind to BSA responsible for quenching of tryptophan fluorescence by the static quenching mechanism. The in vitro cytotoxicity suggested that the copper(II) polymer exhibits cytotoxic effects against the selected tumor cell lines.

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One-dimensional copper(II) coordination polymers bridged both by μ-trans-oxamidates and phenyldicarboxylates: Synthesis, crystal structure and DNA binding studies

Cited by 21 publications

References 49 publications

Synthesis, Structure, Cytotoxic Activities and DNA-Binding Properties of a 1D Copper(II) Complex Bridged both by Oxamidate and Terephthalato Groups

Synthesis, Structure, Cytotoxic Activities and DNA-Binding Properties of a 1D Copper(II) Complex Bridged both by Oxamidate and Terephthalato Groups

Synthesis, characterization, and crystal structure determination of two copper(II) complexes: [Cu(dm4bt)Cl₂(DMSO)] and [{Cu(dm4bt)(H₂O)(tpht)} · H₂O]_n

Synthesis and Structure of a New Copper(II) Coordination Polymer Alternately Bridged by Oxamido and Carboxylate Groups: Evaluation of DNA/BSA Binding and Cytotoxic Activities

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One-dimensional copper(II) coordination polymers bridged both by μ-trans-oxamidates and phenyldicarboxylates: Synthesis, crystal structure and DNA binding studies

Cited by 21 publications

References 49 publications

Synthesis, Structure, Cytotoxic Activities and DNA-Binding Properties of a 1D Copper(II) Complex Bridged both by Oxamidate and Terephthalato Groups

Synthesis, Structure, Cytotoxic Activities and DNA-Binding Properties of a 1D Copper(II) Complex Bridged both by Oxamidate and Terephthalato Groups

Synthesis, characterization, and crystal structure determination of two copper(II) complexes: [Cu(dm4bt)Cl2(DMSO)] and [{Cu(dm4bt)(H2O)(tpht)} · H2O] n

Synthesis and Structure of a New Copper(II) Coordination Polymer Alternately Bridged by Oxamido and Carboxylate Groups: Evaluation of DNA/BSA Binding and Cytotoxic Activities

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Synthesis, characterization, and crystal structure determination of two copper(II) complexes: [Cu(dm4bt)Cl₂(DMSO)] and [{Cu(dm4bt)(H₂O)(tpht)} · H₂O]_n