One-Dimensional Luminous Nanorods Featuring Tunable Persistent Luminescence for Autofluorescence-Free Biosensing

Wang, Jie; Ma, Qinqin; Zheng, Wei; Liu, Haoyang; Yin, Changqing; Wang, Xinghuan; Chen, Xueyuan; Yuan, Quan; Tan, Weihong

doi:10.1021/acsnano.7b03128

Cited by 158 publications

(108 citation statements)

References 53 publications

Supporting

Mentioning

108

Contrasting

Order By: Relevance

“…For example in biomedical applications, LPL materials can be used postexcitation, overcoming any issue of autofluorescence. [ 6–8 ] Currently, the most successful LPL materials make use of transition and rare‐earth metal ions. [ 9,10 ] Although the metals grant exceptionally long afterglows that range from minutes to hours, with some systems lasting days and weeks, [ 11 ] they are not without their inherent drawbacks.…”

Section: Figurementioning

confidence: 99%

Two Are Better Than One: A Design Principle for Ultralong‐Persistent Luminescence of Pure Organics

et al. 2020

View full text Add to dashboard Cite

drawbacks. In addition to the higher material costs of these rare-earth metals, many inorganic LPLs require harsh synthetic procedures, [11] further increasing research costs. Organic LPL (OLPL) materials, [12][13][14][15][16] offer the promise of a multitude of benefits: easier synthesis, easier modification for targeted functionality, and easier processing. However, the development of OLPL materials has encountered many obstacles. To access long lived states in organic compounds, there have been many designs to exploit the excited triplet state. Though access to and from the triplet state is a forbidden process and once thought to be too inefficient for effective use at room temperature, [17] recent advances have vastly increased intersystem crossing efficiency by enhancing spin-orbit coupling (SOC) with the use of heteroatoms, [18,19] the carbonyl functional group, [20][21][22] heavy atom effects, [23][24][25][26][27] and multimer-enhanced intersystem crossing. [28][29][30][31][32] Equally important is protecting the long-lived triplet after its generation, due to the fact that they are particularly sensitive to molecular vibrational quenching and atmospheric oxygen. In this regard, recent works have accomplished this through the use of crystals, [33,34] metal-organic frameworks, [35] H-aggregation, [36] and others. [30,32,37] Although there have been many achievements in generating organic room-temperature Because of their innate ability to store and then release energy, longpersistent luminescence (LPL) materials have garnered strong research interest in a wide range of multidisciplinary fields, such as biomedical sciences, theranostics, and photonic devices. Although many inorganic LPL systems with afterglow durations of up to hours and days have been reported, organic systems have had difficulties reaching similar timescales. In this work, a design principle based on the successes of inorganic systems to produce an organic LPL (OLPL) system through the use of a strong organic electron trap is proposed. The resulting system generates detectable afterglow for up to 7 h, significantly longer than any other reported OLPL system. The design strategy demonstrates an easy methodology to develop organic long-persistent phosphors, opening the door to new OLPL materials.Long-persistent luminescent [1,2] (LPL) materials have demonstrated great potential and performance in multiple areas, such as life sciences, [3] the biomedical field, [2,4] and photo voltaics, [5] as they offer fascinating possibilities for their ability to store and slowly release excited state energy. For example in biomedical applications, LPL materials can be used postexcitation, overcoming any issue of autofluorescence. [6][7][8] Currently, the most successful LPL materials make use of transition and rare-earth metal ions. [9,10] Although the metals grant exceptionally long afterglows that range from minutes to hours, with some systems lasting days and weeks, [11] they are not without their inherentThe ORCID identification number(s) for the aut...

show abstract

Section: Figurementioning

confidence: 99%

Two Are Better Than One: A Design Principle for Ultralong‐Persistent Luminescence of Pure Organics

et al. 2020

View full text Add to dashboard Cite

show abstract

“…There are two mutually contradictory aspects for attaining a nanosized PSL material: on the one hand, high temperature is required to induce suitable deep traps in the host responsible for the charging/releasing of charge carriers (electrons or holes) during data encoding/ decoding and, on the other hand, high temperature is known to result in severe particle coarsening and agglomeration. Few examples have succeeded in achieving PSL in nanosystems 34,35 , let alone considered their viability for large-capacity ODS.…”

Section: Introductionmentioning

confidence: 99%

High-security-level multi-dimensional optical storage medium: nanostructured glass embedded with LiGa5O8: Mn2+ with photostimulated luminescence

et al. 2020

View full text Add to dashboard Cite

The launch of the big data era puts forward challenges for information preservation technology, both in storage capacity and security. Herein, a brand new optical storage medium, transparent glass ceramic (TGC) embedded with photostimulated LiGa 5 O 8 : Mn 2+ nanocrystals, capable of achieving bit-by-bit optical data write-in and read-out in a photon trapping/detrapping mode, is developed. The highly ordered nanostructure enables light-matter interaction with high encoding/decoding resolution and low bit error rate. Importantly, going beyond traditional 2D optical storage, the high transparency of the studied bulk medium makes 3D volumetric optical data storage (ODS) possible, which brings about the merits of expanded storage capacity and improved information security. Demonstration application confirmed the erasable-rewritable 3D storage of binary data and display items in TGC with intensity/ wavelength multiplexing. The present work highlights a great leap in photostimulated material for ODS application and hopefully stimulates the development of new multi-dimensional ODS media.

show abstract

“…From the luminescence spectra of ZGO:Mn with different Mn 2+ (Figure 2a,b and c and Figure S2), the nanorods exhibit maximum excitation at 249 nm and maximum emission wavelength at 533 nm regardless of the different concentrations of Mn 2+ . The green emission at 533 nm is attributed to the escaped electrons moved by the excited energy level of Mn 2+ , resulting in the recombination of the electrons with holes that are generated by the nanorods ZGO:Mn under UV excitation [20]. The insets show photographs of the nanorods which emit strong green luminescence.…”

Section: Characterization Of the Zgo: Mnmentioning

confidence: 99%

“…Firstly, the as-prepared ZGO: Mn was modified using APTES, and the resulting ZGO: Mn-NH 2 was dispersed in ultrapure water [20]. Secondly, avidin-coated ZGO: Mn (ZGO: Mn-Avidin) was synthesized through the addition of glutaraldehyde [37].…”

Section: Surface Modification Of the Zgo: Mnmentioning

confidence: 99%

“…In contrast, the PLNPs can continuously maintain a higher intensity luminescence, thereby avoiding the interference of autofluorescence and improving the signal-to-noise ratio [17,19]. Tan's group has reported the hydrothermal synthesis of Zn 2 GeO 4 :Mn (ZGO:Mn) nanorods of different sizes by adjusting the pH of the system [20]. Unlike traditional solid-phase calcination, ZGO:Mn nanorods prepared using hydrothermal synthesis disperse better in aqueous solutions, which is more suitable for the fabrication of As(III) probes [21].…”

mentioning

confidence: 99%

See 1 more Smart Citation

Construction of Time-Resolved Luminescence Nanoprobe and Its Application in As(III) Detection

Chen

Wang

et al. 2020

Nanomaterials

View full text Add to dashboard Cite

As(III) is a toxic heavy metal which causes serious health problems. Therefore, the development of highly sensitive sensors for As(III) detection is of great significance. Herein, a turn-on luminescence resonance energy transfer (LRET) method based on luminous nanorods was designed for As(III) detection. Biotin-labelled As(III) aptamers were tagged to avidin functionalized luminous nanorods as energy donors, while graphene oxide (GO) acted as the energy acceptor. The adsorption of single-stranded DNA on graphene oxide resulted in the efficient quenching of the luminescence of the nanorods through the LRET process. In the presence of As(III), aptamers bonded to As(III) preferentially and resulted in the formation of aptamer-As(III) complexes. The aptamer-As(III) complexes were rubbed off from the GO surface due to their conformational change, which led to the recovery of the luminescence of the nanorods. A good linear relationship between the luminescence intensity and concentration of As(III) was obtained in the range from 1 to 50 ng·mL −1 , with a detection limit of 0.5 ng·mL −1 . Furthermore, the developed sensors showed good specificity towards As(III) and proved capable of detecting As(III) in the environment and food samples. The proposed time-resolved sensors provide a promising sensing strategy for the rapid and sensitive detection of As(III).Nanomaterials 2020, 10, 551 2 of 12 to bind to specific targets, many scholars have have established a variety of detection methods for hazardous substances in different foods, including biotoxins [11], foodborne pathogens [12], pesticide and veterinary drug residues [13], heavy metals [14,15] and illegal additives [16].'Persistent luminescent nanoparticles' (PLNPs) refers to a series of nanomaterials that can continuously emit luminescence after being excited [17]. Their luminescence decay time ranges from a few microseconds to several hours [18]. Since the autofluorescence lifetime of the complex system is one nanosecond or less, the decay of the background noise will soon be completed after the excitation light is turned off [18]. In contrast, the PLNPs can continuously maintain a higher intensity luminescence, thereby avoiding the interference of autofluorescence and improving the signal-to-noise ratio [17,19]. Tan's group has reported the hydrothermal synthesis of Zn 2 GeO 4 :Mn (ZGO:Mn) nanorods of different sizes by adjusting the pH of the system [20]. Unlike traditional solid-phase calcination, ZGO:Mn nanorods prepared using hydrothermal synthesis disperse better in aqueous solutions, which is more suitable for the fabrication of As(III) probes [21]. Recently, with the development of the theory, more and more optical sensors for As(III) detection based on various principles have been designed [22], including fluorescent [23][24][25][26], colorimetric [27,28], resonance Rayleigh scattering (RRS)-based [29], chemiluminescence-based [30,31] and electrochemical [31] methods. However, there are few reports of the development of As(III) time-resolved luminescence pr...

show abstract

One-Dimensional Luminous Nanorods Featuring Tunable Persistent Luminescence for Autofluorescence-Free Biosensing

Cited by 158 publications

References 53 publications

Two Are Better Than One: A Design Principle for Ultralong‐Persistent Luminescence of Pure Organics

Two Are Better Than One: A Design Principle for Ultralong‐Persistent Luminescence of Pure Organics

High-security-level multi-dimensional optical storage medium: nanostructured glass embedded with LiGa5O8: Mn2+ with photostimulated luminescence

Construction of Time-Resolved Luminescence Nanoprobe and Its Application in As(III) Detection

Contact Info

Product

Resources

About