One of the most frequent vascular diseases in northeastern of Turkey: Thromboangiitis obliterans or Buerger's disease (experience with 344 cases)

Ateş, Azman; Yekeler, İbrahim; Ceviz, Münacettin; Erkut, Bilgehan; Paç, Mustafa; Başoğlu, Ahmet; Koçak, Hikmet

doi:10.1016/j.ijcard.2005.12.002

Cited by 40 publications

(22 citation statements)

References 27 publications

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“…This may be explained by high incidence of inflammatory disease in young adult and strongly related to active heavy smoking habit which is more in young adults. 3,[13][14][15] In the current study, male patient constituted approximately 97.4% of all patients which coincides with all the literature. This explained by high prevalence of smoking in male.…”

Section: Discussionsupporting

confidence: 91%

“…This may be attributed to the nature of the disease and rapid progression of the pathology with relatively high limb loss. 3,[13][14][15][16][17][18][19][20][21] In the current study, associated popliteal artery disease was present in 34.6% of our cases. Graziani and Piaggesi also reported that associated popliteal artery disease was present in 45% of their cases.…”

Section: Discussionsupporting

confidence: 52%

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Management of Buerger's Disease in Endovascular Era

et al. 2019

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This study was aimed to report data on the feasibility, safety, and effectiveness of endovascular procedures in a thromboangiitis obliterans diagnosed patients presenting with critical limb ischemia (CLI). Prospective study conducted on patients affected by Buerger's disease who presented to our center along 2 years. Clinical, radiological, and patient-based outcomes were recorded at 3, 6, and 12 months after the intervention. Total 39 patients were included in the study. Fifteen (38.5%) patients underwent percutaneous transluminal angioplasty, another 15 patients (38.5%) underwent follow-up on medical treatment, there are four other patients (10.3%) underwent surgical bypass, and five (12.8%) patients underwent lumbar sympathectomy. The 12 months' outcome showed 66.7% technical success in endovascular group with 46.7% patency rate (p-value = 0.06), 86.7% limb salvage rate (LSR; p-value < 0.04), and 66.7% clinical improvement (p-value = 0.005). The endovascular management of Buerger's disease is feasible, save, and effective with high rate of LSR and clinical improvement.

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Section: Discussionsupporting

confidence: 91%

Section: Discussionsupporting

confidence: 52%

Management of Buerger's Disease in Endovascular Era

et al. 2019

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“…Second, BD represented pathological Wndings of infectious characters especially in its acute phase lesion where occlusive, highly cellular, inXammatory thrombi and micro abscesses could be observed (Olin 2000;Tanaka 1998). Third, the incidence of BD showed an inverse correlation with the socioeconomic development, because the prevalence of BD has decreased markedly in advanced world such as Western countries and Japan (Kobayashi et al 2006;Olin 2000), but it still is prevalent in South and East Asia, as well as is one of the most frequently vascular diseases in northeastern of Turkey (Ates et al 2006;Iwai et al 2005), and it is generally accepted that the infectious diseases decreases with the socioeconomic development. In addition, we recently reported that BD patients showed signiWcantly elevated serum IgG titers to Treponema denticola (T. denticola) and Actinobacillus actinomycetemcomitans (A. actinomycetemcomitans) as well as to P. gingivalis (Chen et al 2007).…”

Section: Discussionmentioning

confidence: 99%

Synergistic contribution of CD14 and HLA loci in the susceptibility to Buerger disease

et al. 2007

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Buerger disease (BD) is an occulusive vascular disease of unknown etiology. Although cigarette smoking is a well-known risk factor of BD, genetic factors may also play a role in the etiology. Because chronic bacterial infection such as oral periodontitis is suggested to be involved in the pathogenesis of BD, gene polymorphisms involved in the infectious immunity might be associated with BD as the genetic factor(s). We have previously reported that HLA-DRB1*1501 and B54 was associated with BD in Japanese. In this study, polymorphisms in HLA-DPB1, DRB1 and B were analyzed in 131 Japanese BD patients and 227 healthy controls. In addition, we investigated a functional promoter polymorphism, -260 C > T, of CD14 that is a main receptor of bacterial lipopolysaccharide. It was found that the frequencies of CD14 TT genotype [37.4 vs. 24.2%, P = 0.008 OR = 1.87, 95% confidence interval (CI); 1.18, 2.97], DRB1*1501 (34.4 vs. 13.2%, P (c) = 4.4 x 10(-5), OR = 3.44, 95%CI; 2.06, 5.73) and DPB1*0501 (79.4 vs. 55.1%, P (c) = 4.7 x 10(-5), OR = 3.14, 95%CI; 1.93, 5.11) were significantly higher in the patients than in the controls, demonstrating that at least three genetic markers were associated with BD. Stratification analyses of these associated markers suggested synergistic roles of the genetic factors. Odds ratios ranged from 4.72 to 12.57 in individuals carrying any two of these three markers. These findings suggested that the susceptibility to BD was in part controlled by genes involved in the innate and adaptive immunity.

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“…Upper limb sympathetic ablation has been successfully performed for intractable pain, ulceration or gangrene [171][172][173][174]. However, in a recent analysis of 344 cases, the duration of effect was limited, especially if smoking continued [175].…”

Section: Obstructive Ischaemiamentioning

confidence: 99%

Thoracic sympathectomy: a review of current indications

et al. 2015

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Currently, thoracic sympathetic ablation is indicated mainly for primary hyperhidrosis, especially affecting the palm, and to a lesser degree, axilla and face, and for facial blushing. Despite modern pharmaceutical, endovascular and surgical treatments, sympathetic ablation has still a place in the treatment of very selected cases of angina, arrhythmias and cardiomyopathy. Thoracic sympathetic ablation is indicated in several painful conditions: the early stages of complex regional pain syndrome, erythromelalgia, and some pancreatic and other painful abdominal pathologies. Although ischaemia was historically the major indication for sympathetic ablation, its use has declined to a few selected cases of thromboangiitis obliterans (Buerger's disease), microemboli, primary Raynaud's phenomenon and Raynaud's phenomenon secondary to collagen diseases, paraneoplastic syndrome, frostbite and vibration syndrome. Thoracic sympathetic ablation for hypertension is obsolete, and direct endovascular renal sympathectomy still requires adequate clinical trials. There are rare publications of sympathetic ablation for primary phobias, but there is no scientific basis to support sympathetic surgery for any psychiatric indication.

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One of the most frequent vascular diseases in northeastern of Turkey: Thromboangiitis obliterans or Buerger's disease (experience with 344 cases)

Cited by 40 publications

References 27 publications

Management of Buerger's Disease in Endovascular Era

Management of Buerger's Disease in Endovascular Era

Synergistic contribution of CD14 and HLA loci in the susceptibility to Buerger disease

Thoracic sympathectomy: a review of current indications

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