One-Pot Multicomponent Domino Synthesis of 4-Aminothiazole-2(3H)-thiones

Hajibabaei, Khadijeh; Zali‐Boeini, Hassan

doi:10.1055/s-0034-1378922

Cited by 3 publications

(2 citation statements)

References 12 publications

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“…It involves the cyclization of 2‐bromo 2‐arylacetonitrile with primary amines and carbon disulfide (Scheme 19). [50] This strategy also explored the catalytic proficiency of a combination of inexpensive and easily available sodium carbonate and sodium iodide at room temperature. Notably, it was found that the yield chop down on enhancing the temperature to 50 or 70 °C, because of unwanted side reactions.…”

Section: Heterocyclic Compoundsmentioning

confidence: 99%

Multicomponent Approaches Involving Carbon Disulfide

Morja¹,

Viradiya

Chikhalia

2023

Asian J Org Chem

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In present scenario, innovative carbon disulfide‐involving multicomponent protocols are extremely advantageous for practical and efficient construction of acyclic as well as heterocyclic building blocks. Carbon disulfide is well recognized synthetic component and has achieved the desirability of scientific community for the preparation of a variety of highly functionalized organic scaffolds. Carbon disulfide involving MCRs mostly advantage from other features such as bond‐forming efficiency, resource effectiveness, the use of easily obtainable starting compounds, and atom‐economy, which make these protocols useful environmentally benign alternatives, in care with the greener way in which organic chemistry is going on. In this review article, we have discussed the noteworthy topical advances in the promising region of carbon disulfide‐involving multicomponent reactions. It highlight the prospects and confronts, emphasizing the diverse approaches established previously.

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Section: Heterocyclic Compoundsmentioning

confidence: 99%

Multicomponent Approaches Involving Carbon Disulfide

Morja¹,

Viradiya

Chikhalia

2023

Asian J Org Chem

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“…Finally, an acceptor accomplishes the intramolecular cyclization to give 10.1 . The use of esters, 13` b c acids, 13d ketones, 13e f and nitriles, 13g as the acceptor have all been studied. This represents a facile route to thiazolidine heterocycles, as usually no catalyst or additive base is required.…”

Section: Reactions With Electrophilesmentioning

confidence: 99%

A Decade of Advances of CS2/Amines in Three-Component Reactions

Wang

et al. 2022

Synthesis

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Carbon disulfide (CS2) and amines are widely used in three-component reactions. Commonly, dithiocarbamic acids will be generated. As intermediates, dithiocarbamic acids are able to react with electrophiles, or nucleophiles. The goal of this review is to present an overview of CS2/amines in organic synthesis. It focuses on reactions with alkenes, alkynes, I2, arynes, allenes, quinones, vinyl chlorides, aryl halides, aryl boronic acids, 2-iodoanilines, 2-aminophenols, hypervalent iodines, epoxide, or maleic anhydride.

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