One-pot multistep synthesis of 1-fluoroalkylisoquinolines and fused fluoroalkylpyridines from <i>N</i>-fluoroalkyl-1,2,3-triazoles

Kubíčková, Anna; Voltrová, Svatava; Kleman, Adam; Klepetářová, Blanka; Beier, Petr

doi:10.1039/d4qo00713a

Org. Chem. Front.

2024

DOI: 10.1039/d4qo00713a

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One-pot multistep synthesis of 1-fluoroalkylisoquinolines and fused fluoroalkylpyridines from N-fluoroalkyl-1,2,3-triazoles

Anna Kubíčková,

Svatava Voltrová,

Adam Kleman

et al.

Abstract: Microwave heating of N-fluoroalkyl-1,2,3-triazoles proceeding via ketenimines and difluoroazadienes provided 1-fluoroalkyl-3-fluoroisoquinolines.

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Transformation of 5-acylated N-fluoroalkyl-1,2,3-triazoles to trifluoromethylated ring-fused isoquinolines, 1,3-oxazines, and 1,3-oxazin-6-ones via ketenimines

Janecký,

Klepetářová,

Beier

2024

RSC Adv.

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Transformation of 5-acylated N-fluoroalkyl-1,2,3-triazoles to trifluoromethylated ring-fused isoquinolines, 1,3-oxazines, and 1,3-oxazin-6-ones via ketenimines

Janecký,

Klepetářová,

Beier

2024

RSC Adv.

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show abstract

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One-pot multistep synthesis of 1-fluoroalkylisoquinolines and fused fluoroalkylpyridines from N-fluoroalkyl-1,2,3-triazoles

Abstract: Microwave heating of N-fluoroalkyl-1,2,3-triazoles proceeding via ketenimines and difluoroazadienes provided 1-fluoroalkyl-3-fluoroisoquinolines.

Cited by 1 publication

References 36 publications

Transformation of 5-acylated N-fluoroalkyl-1,2,3-triazoles to trifluoromethylated ring-fused isoquinolines, 1,3-oxazines, and 1,3-oxazin-6-ones via ketenimines

Transformation of 5-acylated N-fluoroalkyl-1,2,3-triazoles to trifluoromethylated ring-fused isoquinolines, 1,3-oxazines, and 1,3-oxazin-6-ones via ketenimines

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