One pot synthesis of benzyltriphenylphosphonium acetates from the corresponding activated benzylic alcohols

Abstract

A simple synthetic methodology for the preparation of benzyltriphenylphosphonium acetates is described. The reaction, using different benzyl alcohols substituted with an electron-donating group, involves the generation of a good leaving group and substitution with triphenylphosphine. In these cases the reactions take place with good yields. Furthermore, the obtained salts (16 and 17) have been used for the synthesis of 5-substituted benzofuroxan derivatives.