One-pot synthesis of biocompatible superparamagnetic iron oxide nanoparticles/hydrogel based on salep: Characterization and drug delivery

Bardajee, Ghasem Rezanejade; Hooshyar, Zari

doi:10.1016/j.carbpol.2013.10.028

Cited by 53 publications

(26 citation statements)

References 76 publications

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“…Gold‐polymer nanoshell, gold‐silica nanoshell, and magnetic NPs have also been developed for the purpose of photothermally modulating drug delivery. Locally generated heat from exposure to NIR is used to trigger swelling/dwelling of the hydrogel network and results in the release of entrapped therapeutic payloads.…”

Section: Personalizing Hydrogels Via Multifunctional Nanomaterialsmentioning

confidence: 99%

Personalizing Biomaterials for Precision Nanomedicine Considering the Local Tissue Microenvironment

Oliva

Unterman

Zhang

et al. 2015

Adv Healthcare Materials

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New advances in (nano)biomaterial design coupled with the detailed study of tissue-biomaterial interactions can open a new chapter in personalized medicine, where biomaterials are chosen and designed to match specific tissue types and disease states. The notion of a "one size fits all" biomaterial no longer exists, as growing evidence points to the value of customizing material design to enhance (pre)clinical performance. The complex microenvironment in vivo at different tissue sites exhibits diverse cell types, tissue chemistry, tissue morphology, and mechanical stresses that are further altered by local pathology. This complex and dynamic environment may alter the implanted material's properties and in turn affect its in vivo performance. It is crucial, therefore, to carefully study tissue context and optimize biomaterials considering the implantation conditions. This practice would enable attaining predictable material performance and enhance clinical outcomes.

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Section: Personalizing Hydrogels Via Multifunctional Nanomaterialsmentioning

confidence: 99%

Personalizing Biomaterials for Precision Nanomedicine Considering the Local Tissue Microenvironment

Oliva

Unterman

Zhang

et al. 2015

Adv Healthcare Materials

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“…However, the excellent properties of these materials when compared with their bulk counterparts provide a very promising future for their use in this field [1,2]. Among many nanomaterials investigated, systems made from magnetic iron oxide nanoparticles (MIONPs), proved to be useful in variety applications such as ferrofluids [3], magnetic resonance imaging (MRI) [4], biological cell labeling [5], sorting and separation of biochemicals [6], drug delivery [7], and the treatment of waste waters [8,9]. Moreover, these NPs are known to be capable of sorption of some ligands, dyes, metal ions, anions, cations and use of them is thus becoming very attractive in a new area of adsorption, recovery or removal of some ions [10][11][12][13].…”

Section: Introductionmentioning

confidence: 99%

Surface modified magnetic nanoparticles as efficient and green sorbents: Synthesis, characterization, and application for the removal of anionic dye

Rajabi

Arjmand

Hoseini

et al. 2015

Journal of Magnetism and Magnetic Materials

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“…MNPs exhibit the phenomenon of superparamagnetism which can be utilized for in vitro or in vivo applications. [17][18][19][20] They can be held at the target site for a controlled treatment period, under the influence of an external magnetic field. 8,9 If an alternating magnetic field is applied to the magnetic material, its magnetization will trace out a loop called a hysteresis loop.…”

Section: Introductionmentioning

confidence: 99%

“…15,16 Magnetic targeted drug delivery is a physical method of delivering suitably surface modified nanomicrosize magnetic particles, loaded with a drug, to a target a specific organ, region or a localized disease site. [17][18][19][20] They can be held at the target site for a controlled treatment period, under the influence of an external magnetic field. This is an efficient method as it can achieve pin point delivery of very high concentrations of chemotherapeutic agents directly at the target site only, such as a tumor.…”

Section: Introductionmentioning

confidence: 99%

Synthesis and Characterization of Magnetite/Polyvinyl Alcohol Core–Shell Composite Nanoparticles

2014

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Magnetite (Fe3O4)/polyvinyl alcohol (PVA) core–shell composite nanoparticles were successfully synthesized using a coprecipitation of ferrous and ferric chloride followed by coating with PVA. The resulting nanoparticles were characterized using X‐ray diffraction, Fourier Transform Infrared Spectroscopy, Transmission Electron Microscopy, X‐ray photo electron spectroscopy, Zeta potential measurements, UV–Vis spectroscopy, Thermogravimetric Analysis, and Vibrating Sample Magnetometry (VSM). The average particle size was 13 nm. The presence of characteristic functional groups of PVA around the core of magnetite nanoparticles was confirmed by FTIR spectroscopy while the amount of PVA (%) bound to it was estimated by TGA analysis. Zeta potential measurements made by dispersing dilute sonicated samples in a Phosphate Buffer Saline (PBS pH 7.4) confirmed that the particles were negatively charged. The stability and retention of the coating material PVA in PBS (pH7.4) over a period of time were substantiated by UV–Vis spectroscopy. Room‐temperature magnetic measurements were made with a VSM which demonstrated the superparamagnetic nature of the particles with higher saturation magnetization of 56.41 emu/g. Furthermore, in vitro cytocompatibility testing of Fe3O4/PVA core–shell composite nanoparticles was carried out on human cervix cancer cells. This confirmed a 97% cell viability with no significant cytotoxicity and thereby substantiated their biocompatibility.

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One-pot synthesis of biocompatible superparamagnetic iron oxide nanoparticles/hydrogel based on salep: Characterization and drug delivery

Cited by 53 publications

References 76 publications

Personalizing Biomaterials for Precision Nanomedicine Considering the Local Tissue Microenvironment

Personalizing Biomaterials for Precision Nanomedicine Considering the Local Tissue Microenvironment

Surface modified magnetic nanoparticles as efficient and green sorbents: Synthesis, characterization, and application for the removal of anionic dye

Synthesis and Characterization of Magnetite/Polyvinyl Alcohol Core–Shell Composite Nanoparticles

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