One-pot synthesis of imines by direct coupling of alcohols and amines over magnetically recoverable CdFe2O4 nanocatalyst

Vinuthna, Ch.; Raju, S.; Lingareddy, Eeda; Raju, D. Siva

doi:10.1016/j.matlet.2021.130417

Cited by 8 publications

(1 citation statement)

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“…In recent years, various oxidizing and nucleophilic compounds have been employed in TOP reactions 39 , 40 . Further, TOP has been extended to include multicomponent reactions (MCRs), enabling the synthesis of diverse valuable compounds 41 – 43 . These processes provide a high atom economy, reducing the need for time-consuming, expensive, waste-generating operations, and purification processes in chemical synthesis 44 .…”

Section: Introductionmentioning

confidence: 99%

Advances in the greener synthesis of chromopyrimidine derivatives by a multicomponent tandem oxidation process

Ghamari Kargar,

Bagherzade

2023

Sci Rep

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A hydrophilic cobalt/copper heterogeneous bimetallic catalyst named mTEG-CS-Co/Cu-Schiff-base/IL was successfully synthesized from chitosan polysaccharide. The new catalyst was investigated and confirmed using various techniques including FT-IR, FE-SEM, EDX-EDS, XRD, TEM, TGA, AFM, NMR and ICP. The catalyst exhibited powerful catalyst activity for the tandem one pot oxidative chromopyrimidine reaction from benzyl alcohols under mild conditions, utilizing air as a clean source in a green protocol. The catalyst was compatible with a wide range of benzyl alcohols, and aldehydes formed in situ, and bis-aldehydes synthesized were condensed with urea/4‑hydroxycumarin to provide favorable products in good yields for all derivatives (14 new derivatives). The presence of tri-ethylene glycol and imidazolium moieties with hydrophilic properties on the mTEG-CS-Co/Cu-Schiff-base/IL nanohybrid provides dispersion of the nanohybrid particles in water, leading to higher catalytic performance. Furthermore, the reaction exhibited several other notable features, including low catalyst loading, the ability to be recycled for up to 6 stages, high atom economy, a simple work procedure, short reaction time, utilization of an environmentally friendly nanohybrid, and the replacement of volatile and organic solvents with water solvent.

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