One-pot synthesis of mesoporous structured ratiometric fluorescence molecularly imprinted sensor for highly sensitive detection of melamine from milk samples

Xu, Shoufang; Lu, Hongzhi

doi:10.1016/j.bios.2015.05.064

Cited by 91 publications

(22 citation statements)

References 27 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Notably, melamine in milk samples displayed more than 90% recovery. In a similar fashion, Xu and co-workers reported the molecularly-imprinted CdTe QDs for ratiometric discrimination of melamine [40]. As shown in Figure 4, these MIP@CdTe QDs were synthesized in a single step and then utilized in ratiometric identification of melamine.…”

Section: Carbon and Quantum Dots For Melamine Detectionmentioning

confidence: 81%

See 1 more Smart Citation

Review on Nanomaterial-Based Melamine Detection

Shellaiah

Sun

2019

Chemosensors

View full text Add to dashboard Cite

Illegal adulteration of milk products by melamine and its analogs has become a threat to the world. In 2008, the misuse of melamine with infant formula caused serious effects on babies of China. Thereafter, the government of China and the US Food and Drug Administration (FDA) limited the use of melamine of 1 mg/kg for infant formula and 2.5 mg/kg for other dairy products. Similarly, the World Health Organization (WHO) has also limited the daily intake of melamine of 0.2 mg/kg body weight per day. Many sensory schemes have been proposed by the scientists for carrying out screening on melamine poisoning. Among them, nanomaterial-based sensing techniques are very promising in terms of real-time applicability. These materials uncover and quantify the melamine by means of diverse mechanisms, such as fluorescence resonance energy transfer (FRET), aggregation, inner filter effect, surface-enhanced Raman scattering (SERS), and self-assembly, etc. Nanomaterials used for the melamine determination include carbon dots, quantum dots, nanocomposites, nanocrystals, nanoclusters, nanoparticles, nanorods, nanowires, and nanotubes. In this review, we summarize and comment on the melamine sensing abilities of these nanomaterials for their suitability and future research directions.

show abstract

Section: Carbon and Quantum Dots For Melamine Detectionmentioning

confidence: 81%

“…Schematic illustration for the one pot preparation of mesoporous structured ratiometric fluorescence of molecularly-imprinted polymers (MIPs) probe (reproduced with permission from Reference[40]). …”

mentioning

confidence: 99%

Review on Nanomaterial-Based Melamine Detection

Shellaiah

Sun

2019

Chemosensors

View full text Add to dashboard Cite

show abstract

“…Fluorescent sensors provide a promising method for the detection of trace pollutants because such methods are simple, rapid, and have high sensitivity and selectivity [33,34]. The use of combinations of MIPs and fluorescence assays to detect melamine in milk and infant formula milk powder has been reported [35][36][37]. Fluorescent MIP sensors can be divided into two categories based on their preparation method.…”

Section: Introductionmentioning

confidence: 99%

Development of ELISA-Like Fluorescence Assay for Melamine Detection Based on Magnetic Dummy Molecularly Imprinted Polymers

et al. 2018

View full text Add to dashboard Cite

We present a directly competitive fluorescence assay for highly sensitive detection of melamine in milk using magnetic dummy molecularly imprinted polymers (MDMIPs). The detection principle is based on competitive binding between the fluorescent label and melamine on the MDMIPs. The fluorescent label was obtained by combining fluorescein isothiocyanate (FITC) with melamine in ethanol and water. MDMIPs were prepared on the surface of Fe 3 O 4 @SiO 2 nanoparticles using 2,4-diamino-6-methyl-1,3,5-triazine as dummy template. The MDMIPs were characterized and their adsorption capacity was evaluated based on their static adsorption and Scatchard analysis. Results suggest that MDMIPs were successfully coated on the Fe 3 O 4 @SiO 2 surface and had a core-shell structure. Adsorption experiments suggested that the MDMIPs had higher specific recognition capacities for melamine and FITC-melamine (FITC-Mel) than did magnetic dummy molecularly non-imprinted polymers. Competitive binding between FITC-Mel and melamine was performed under the optimum conditions to determine melamine quantitatively. The linear range of this fluorescence assay was 0.1-20 mg/L for melamine detection. The detection limit was 0.05 mg/L in negative milk samples. The assay was also successfully employed to detect melamine in spiked milk samples, with satisfactory recoveries, i.e., between 70.2% and 92.7%.

show abstract

“…Detection of analyte molecules by fabricating QDs has become a promising method in biological science. MIPs coated QDs sensors have been used for detection of amoxicillin [11], melamine [12], hemoglobin [13] and cytochrome c [14]. However, most work has used CdTe QDs, which displayed high cytotoxicity [15,16].…”

Section: Introductionmentioning

confidence: 99%

Fluorescent Nanosensor based on Molecularly Imprinted Polymers Coated on Graphene Quantum Dots for Fast Detection of Antibiotics

Zhou

Halder²,

Sun

2018

Preprint

View full text Add to dashboard Cite

In this work, we firstly explored a mild, clean, and highly efficient approach for the synthesis of graphene quantum dots (GQDs). GQDs with carboxyl groups or amino groups, were prepared from one-pot environmentally friendly method assisted by hydrogen peroxide, respectively. It was proved that carboxyl groups played an important role in the fluorescence quenching. Based on these findings, we developed a novel fluorescent nanosensor by combining molecularly imprinted polymers (MIPs) with carboxyl functionalized GQDs for the determination of tetracycline (TC) in aqueous samples. The nanocomposite was prepared using a sol-gel process. GQDs-MIPs showed strong ﬂuorescent emission at 410 nm when excited at 360 nm, which was subsequently quenched in the presence of TC. Under optimum conditions, the fluorescence intensity of GQDs-MIPs decreased in response to the increase of TC concentration with good linearity rage of 1.0-104 µg L-1. The limit of detection was determined to be 1 µg L-1. The fluorescence intensity of GQDs-MIPs was more strongly quenched by TC compared to the corresponding non-imprinted polymers, GQDs-NIPs. With the high sensitivity, the material was also successfully worked for the detection of TC in real spiked milk samples.

show abstract

One-pot synthesis of mesoporous structured ratiometric fluorescence molecularly imprinted sensor for highly sensitive detection of melamine from milk samples

Cited by 91 publications

References 27 publications

Review on Nanomaterial-Based Melamine Detection

Review on Nanomaterial-Based Melamine Detection

Development of ELISA-Like Fluorescence Assay for Melamine Detection Based on Magnetic Dummy Molecularly Imprinted Polymers

Fluorescent Nanosensor based on Molecularly Imprinted Polymers Coated on Graphene Quantum Dots for Fast Detection of Antibiotics

Contact Info

Product

Resources

About