One pot synthesis of thiol-functional nanoparticles

Abstract

Polysorbate 80 (PS80) was reacted with 3-mercaptopropyl trimethoxysilane (SiSH) via a photoinitiated thiol-ene reaction. The conjugate was then mixed with SiSH and water to form uniform thiol-functional nanoparticles (TFNs) approximately...

PISA printing from CTA functionalized polymer scaffolds

“…[24][25][26][27][28] Our initial work on RAFT PISA printing utilized a difunctional poly(ethylene glycol) (PEG) macro-CTA, chain extended with diacetone acrylamide (DAAm) in water, and 3D printed via DLP using lithium phenyl-2,4,6-trimethylbenzoylphosphinate (LAP) as a photo-initiator and phenol red as a photoabsorber. 29 In this study, we observed the dissolution behavior of DAAm PISA frogs in N,N-dimethylformamide (DMF), noting that those without N′N-methylene bisacrylamide (MBAc) crosslinker dissolved completely, indicating the presence of physical crosslinks. Building on this foundation, our second PISA printing study aimed to develop formulations capable of dissolving in physiological fluids with controlled kinetics.…”