One-Stop Shopping: Dual-Energy CT for the Confident Diagnosis of                    Adrenal Adenomas

Hindman, Nicole; Megibow, Alec J.

doi:10.1148/radiol.2020201718

Cited by 5 publications

(3 citation statements)

References 10 publications

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“…Dual-energy CT (either single or dual-source) allows the generation of virtual non-contrast (VNC) images, monochromatic images and material density images [44,45]. The attenuation values obtained with VNC images correlate with those obtained in true unenhanced images, but there is some degree of discordance (in the range of 5-10 HU), thus limiting the adoption of the usual ±10 HU threshold for characterization purposes (Figure 5) [46,47]. For the diagnosis of lipid-rich AA, VNC using the usual cut-off of 10 HU using an acquisition performed between 70 and 100 s after intravenous administration of iodinated material yields 71% sensitivity, similar to single-phase CT [48].…”

Section: Computed Tomographymentioning

confidence: 99%

“…For differentiating between AA and adrenal metastases, the mean iodine density-to-VNC ratio is greater in AA than in metastases because of their maximal iodine uptake during the portal phase (14.5 vs. 4.6; p < 0.001) [46]. Dual-energy CT (either single or dual-source) allows the generation of virtual noncontrast (VNC) images, monochromatic images and material density images [47,48]. The attenuation values obtained with VNC images correlate with those obtained in true unenhanced images, but there is some degree of discordance (in the range of 5-10 HU), thus limiting the adoption of the usual ±10 HU threshold for characterization purposes (Figure 5) [49,50].…”

Section: Computed Tomographymentioning

confidence: 99%

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Adrenal Mass Characterization in the Era of Quantitative Imaging: State of the Art

Barat

Gaujoux

Tenenbaum

et al. 2022

Cancers

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Detection and characterization of adrenal lesions have evolved during the past two decades. Although the role of imaging in adrenal lesions associated with hormonal secretion is usually straightforward, characterization of non-functioning adrenal lesions may be challenging to confidently identify those that need to be resected. Although many adrenal lesions can be readily diagnosed when they display typical imaging features, the diagnosis may be challenging for atypical lesions. Computed tomography (CT) remains the cornerstone of adrenal imaging, but other morphological or functional modalities can be used in combination to reach a diagnosis and avoid useless biopsy or surgery. Early- and delayed-phase contrast-enhanced CT images are essential for diagnosing lipid-poor adenoma. Ongoing studies are evaluating the capabilities of dual-energy CT to provide valid virtual non-contrast attenuation and iodine density measurements from contrast-enhanced examinations. Adrenal lesions with attenuation values between 10 and 30 Hounsfield units (HU) on unenhanced CT can be characterized by MRI when iodinated contrast material injection cannot be performed. 18F-FDG PET/CT helps differentiate between atypical benign and malignant adrenal lesions, with the adrenal-to-liver maximum standardized uptake value ratio being the most discriminative variable. Recent studies evaluating the capabilities of radiomics and artificial intelligence have shown encouraging results.

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Section: Computed Tomographymentioning

confidence: 99%

Section: Computed Tomographymentioning

confidence: 99%

Adrenal Mass Characterization in the Era of Quantitative Imaging: State of the Art

Barat

Gaujoux

Tenenbaum

et al. 2022

Cancers

View full text Add to dashboard Cite

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“…Adrenal adenomas are the most common adrenal tumors, and about 70% of adenoma cells contain intracellular lipids (11,12). Adrenal adenomas are divided into functional and non-functional types.…”

Section: Differential Diagnosis Of Adrenal Teratoma and Other Fatty T...mentioning

confidence: 99%

Teratoma of the adrenal gland: clinical experience and literature review

Yang

Wang

et al. 2020

Gland Surg

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Teratoma originates from pluripotent cells of two or more than two germ cell layers, and most of them are benign. Teratomas are found in the ovaries and testes. Retroperitoneal teratoma is rare, especially adrenal teratoma. Here, we describe a rare case of a 17-year-old woman who was diagnosed with pulmonary tuberculosis and a right adrenal mass at the age of eight. So, she received anti-tuberculosis treatment. Nine years later, chest X-rays showed prior lesions in both lungs, and abdominal CT showed the mass in the right adrenal gland was larger than before, during this period she had no clinical symptoms. She underwent retroperitoneal laparoscopic adrenalectomy, and the pathological diagnosis was a mature teratoma of the right adrenal gland. During a one-year follow-up, the patients recovered well without any discomfort.Thirty-two cases were found in the literature review, among which no patients had a history of pulmonary tuberculosis. Adrenal teratoma is often seen in females and the left adrenal gland. The imaging features of adrenal teratoma can be cystic, solid, and cystic solids. Mature fat and calcification can be seen in most teratomas. Comprehensive analysis of clinical features and imaging characteristics can enhance the diagnostic confidence of radiologists in adrenal teratoma.

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Quantitative dual-energy CT techniques in the abdomen

et al. 2021

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One-Stop Shopping: Dual-Energy CT for the Confident Diagnosis of Adrenal Adenomas

Abstract: Disclosures of Conflicts of Interest: N.M.H. disclosed no relevant relationships. A.J.M. disclosed no relevant relationships.

Cited by 5 publications

References 10 publications

Adrenal Mass Characterization in the Era of Quantitative Imaging: State of the Art

Adrenal Mass Characterization in the Era of Quantitative Imaging: State of the Art

Teratoma of the adrenal gland: clinical experience and literature review

Quantitative dual-energy CT techniques in the abdomen

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