An efficient actuation technique for electrostatic MEMS actuators exploiting electro-mechanical-mechanical modal interactions is proposed. The flexural–torsional equations of motion are established, and we manifest that the initiation of a 2:1 autoparametric modal interaction between in-plane bending and torsional modes of the actuator that is supposed to be symmetrical with respect to its axis of rotation is contingent upon the presence of a quadratic stiffness term, which arises from the existence of non-zero first moments of area of the actual cross-section in prismatic microbeams. In order to efficiently reduce the AC voltage value required to reach the activation of the 2:1 mechanical modal interaction, the electrical resonant frequency is syntonized to half of the natural frequency of the in-plane bending mode. The results indicate that the amplitude of the in-plane motion saturates upon the initiation of an energy exchange between the bending and torsional motions. Through suitable tuning of the AC frequency, the amplitude of the in-plane motion is minimized, while the amplitude of the torsional motion, the indirectly excited mode, is maximized. Our results demonstrate that the actuator's torsional motion, when subjected to a 1:2:1 electro-flexural–torsional modal interactions, is triggered by applying a maximum voltage of 10 V, resulting in about 20 degrees rotational angle. Furthermore, prolific frequency combs are generated as a result of secondary Hopf bifurcations along the large-amplitude response branches, inducing quasi-periodicity in the MEMS dynamics.