One-year claims analysis comparing inhaled fluticasone propionate with zafirlukast for the treatment of asthma

Stempel, David A.; Meyer, Jay W.; Stanford, Richard H.; Yancey, Steve

doi:10.1067/mai.2001.112029

Cited by 38 publications

(13 citation statements)

References 20 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…It is interesting to note in the propensity score analysis that the patients using LMs had significantly higher use of all other medications except for oral short-acting beta 2 -agonists and cromolyn and had higher rates of status asthmaticus. This concurs with other cost-effectiveness research using retrospective claims analysis, which found that, at baseline, the LM users were potentially more severe asthmatics 22,[42][43][44][45] although 2 studies found that the LMs were potentially used less by severe asthmatics. 46,47 All of these studies did attempt to control for base- line differences; however, there were fewer covariates used than used in the present propensity analysis.…”

Section: Discussionsupporting

confidence: 70%

“…Perhaps because of the better ability for a propensity analysis to control for selection bias, our study does not support others that found an increase in emergency room visits and hospitalizations in patients using LMs. 45,22 Indeed, a prospective, longitudinal study of 349 asthma patients showed that patients receiving LMs had more severe asthma, which suggests that great care must be taken to control for selection bias. 48 It is interesting that a significant predictor of LM use was allergies (odds ratio [OR] 1.47; 95% CI, 1.26-1.73).…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Analysis of the Effectiveness and Cost Benefit of Leukotriene Modifiers in Adults With Asthma in the Ohio Medicaid Population

Heaton¹,

Guo²,

Hornung³

et al. 2006

JMCP

View full text Add to dashboard Cite

Section: Discussionsupporting

confidence: 70%

Section: Discussionmentioning

confidence: 99%

Analysis of the Effectiveness and Cost Benefit of Leukotriene Modifiers in Adults With Asthma in the Ohio Medicaid Population

Heaton¹,

Guo²,

Hornung³

et al. 2006

JMCP

View full text Add to dashboard Cite

“…Forty-two subjects with a history of bronchial asthma in the preceding 12 months were selected from two villages with the same low socioeconomic status and asthma prevalence as previously reported [10]. Twenty-one individuals, 10 males and 11 females, aged between 6 and 35 years, were selected from a rural area in the inner state (group I) and another 21 subjects, age- and sex-matched with group I subjects, were selected from a slum close to the sea in Salvador, the capital of the state of Bahia (group II).…”

Section: Subjects Materials and Methodsmentioning

confidence: 99%

Association between Mite Allergen (Der p 1, Der f 1, Blo t 5) Levels and Microscopic Identification of Mites or Skin Prick Test Results in Asthmatic Subjects

Medeiros

Figueiredo

Almeida

et al. 2002

Int Arch Allergy Immunol

View full text Add to dashboard Cite

Background: Mite allergens have been involved in airway sensitization and allergic diseases. Immunoassays for the identification and quantifiction of house dust mite (HDM) allergens are useful to improve the knowledge of regional mite fauna and the remediation of mite allergens in allergic diseases. The present study analyzed the association between levels of HDM allergen and results of mite identification or skin prick test (SPT) in two different areas of Bahia, Brazil. Methods: Forty-two asthmatic subjects from a rural area (group I; n = 21) and a slum (group II; n = 21) were evaluated through SPT with HDM allergens and had dust samples collected at their homes for mite identification and allergen measurements. Results: Positive SPT to Dermatophagoides pteronyssinus, Dermatophagoides farinae and Blomia tropicalis allergens were observed in 42.9, 38.0 and 42.9% subjects from group I and in 47.6, 19.0 and 33.3% subjects from group II, respectively. D. pteronyssinus and B. tropicalis were identified in approximately 76 and 50% of samples from both groups, respectively. D. farinae was identified in 38.0 and 9.5% of samples from groups I and II, respectively (p < 0.005). Der p 1, Der f 1 and Blo t 5 detection were associated with mite identification (p < 0.05). Association between HDM allergen levels over 2 µg/g of dust and positive SPT occurred only with D. pteronyssinus (p < 0.0001). Conclusions:D. pteronyssinus was the most prevalent mite species in this study followed by B. tropicalis and D. farinae. Immunoassays done to measure mite allergens were associated with mite-species identification. We conclude that these three mite species must be included on panels for the diagnosis of allergic airway diseases in subjects living in such regions.

show abstract

“…Several studies have been conducted comparing ICSs with leukotriene modifiers [46][47][48]. Most of these studies have demonstrated better outcomes associated with ICSs.…”

Section: Economic Outcomesmentioning

confidence: 98%

Outcomes associated with inhaled corticosteroid use in asthma and COPD: an update

Bhosle

Shenolikar

Kulkarni

et al. 2004

Expert Review of Pharmacoeconomics & Outcomes Research

View full text Add to dashboard Cite

The aim of this review is to report the updates in the medical literature on the outcomes associated with inhaled corticosteroid use. This update finds that inhaled corticosteroids remain a frontline choice as controller therapy in the treatment of asthma. Adherence to medications, especially inhaled corticosteroids used as controller medications, is responsible for a decrease in hospital, emergency room and physician visits. All of these translate to reduced asthma-related healthcare costs and an increase in health-related quality of life. There is a need for further research on the role of inhaled corticosteroids in chronic obstructive pulmonary disease outcomes.

show abstract

One-year claims analysis comparing inhaled fluticasone propionate with zafirlukast for the treatment of asthma

Cited by 38 publications

References 20 publications

Analysis of the Effectiveness and Cost Benefit of Leukotriene Modifiers in Adults With Asthma in the Ohio Medicaid Population

Analysis of the Effectiveness and Cost Benefit of Leukotriene Modifiers in Adults With Asthma in the Ohio Medicaid Population

Association between Mite Allergen (Der p 1, Der f 1, Blo t 5) Levels and Microscopic Identification of Mites or Skin Prick Test Results in Asthmatic Subjects

Outcomes associated with inhaled corticosteroid use in asthma and COPD: an update

Contact Info

Product

Resources

About