One-year myopia control efficacy of spectacle lenses with aspherical lenslets

Bao, Jinhua; Yang, Adeline; Huang, Yingying; Li, Xue; Pan, Yiguo; Ding, Chenglu; Lim, Ee Woon; Zheng, Jingwei; Spiegel, D.; Drobe, Björn; Liu, Fan; Chen, Hao

doi:10.1136/bjophthalmol-2020-318367

Cited by 95 publications

(170 citation statements)

References 33 publications

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“…Both lenses consist of the same configuration of 11 concentric rings of aspherical lenslets centred on a 9 mm‐diameter clear central zone. Detailed description of the two lenses have been provided elsewhere 23 . A conventional single vision lens was used as a control.…”

Section: Methodsmentioning

confidence: 99%

“…Among children completing a 2‐year study, a lens with defocus incorporated multiple segments (DIMS) slowed myopic progression by around 0.4 D and axial elongation around 0.3 mm 22 . One‐year results from a large randomised clinical trial demonstrated 0.53 D and 0.33 D slowing of myopia progression, and 0.23 mm and 0.11 mm slowing of axial elongation with spectacle lenses containing Highly Aspherical Lenslets (HAL) and Slightly Aspherical Lenslets (SAL), respectively 23 . Both lenses consist of the same configuration of 11 concentric rings of aspherical lenslets centred on a 9 mm‐diameter clear central zone.…”

Section: Introductionmentioning

confidence: 99%

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The impact of spectacle lenses for myopia control on visual functions

Gao¹,

Lim²,

Yang³

et al. 2021

Ophthalmic Physiologic Optic

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Purpose Spectacle lenses containing multiple small peripheral elements have been developed for myopia control in children. It is important that their effect on vision be quantified by (i) fixation through the peripheral portion, thereby using foveal vision and (ii) by fixation through the central portion and presentation of peripheral targets. Methods The above approaches were used in five studies to evaluate two novel spectacle lens designs: spectacle lenses with Highly Aspherical Lenslets (HAL) and Slightly Aspherical Lenslets (SAL). A single vision lens served as a control. Visually normal adults participated in each study. The first two studies had subjects fixate through the periphery of the lenses. High and low (10%) contrast visual acuity was measured with the Freiburg Vision Test and reading speed for high and low contrast words measured with a sentence generator. The other three studies assessed peripheral vision while subjects fixated through the central portion of the lens. Peripheral contrast sensitivity was measured using two cycles per degree drifting Gabor stimuli. Peripheral motion perception was further evaluated using random dot stimuli. Finally, attention was measured using an established test of useful field of view with three levels of complexity. Results The periphery of the HAL lens significantly reduced low contrast visual acuity, but not high contrast visual acuity, while the effect of the SAL lens was not significant for either. Neither test lens affected reading speed for high contrast words, but the HAL lens significantly affected performance for low contrast words. Neither test lens affected peripheral motion perception or useful field of view. Conclusions Low contrast visual acuity and reading was slightly reduced while high contrast visual acuity was unaffected when fixating through the periphery of the novel lens designs. None of the peripheral measures of vision was affected by the novel lens designs.

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Section: Methodsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

The impact of spectacle lenses for myopia control on visual functions

Gao¹,

Lim²,

Yang³

et al. 2021

Ophthalmic Physiologic Optic

Self Cite

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“…There are several optical interventions such as orthokeratology, bifocal spectacles, and multifocal contact lenses ( Huang et al, 2016 ; Wildsoet et al, 2019 ) available in the clinic for myopia control. Recently, spectacle lens designs using lenslets to create a myopia control signal in the periphery, for example, the Defocus Incorporated Multiple Segments (DIMS) ( Lam et al, 2019 ), spectacle lenses with slightly aspherical lenslets (SAL), and spectacle lenses with highly aspherical lenslets (HAL), have shown a promising myopia control effect ( Bao et al, 2021 ). The efficacy of these spectacle lenses was comparable to orthokeratology ( Li et al, 2016 ; Santodomingo-Rubido et al, 2017 ) and 0.01% atropine ( Diaz-Llopis and Pinazo-Duran, 2018 ; Kinoshita et al, 2018 ).…”

Section: Introductionmentioning

confidence: 99%

Influence of Lenslet Configuration on Short-Term Visual Performance in Myopia Control Spectacle Lenses

Xue

Ding

et al. 2021

Front. Neurosci.

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Purpose: This study aimed to evaluate short-term visual performance and optical quality of three different lenslet configurations on myopia control spectacle lenses.Materials and Methods: This study utilized a cross-over design. Distance visual acuity (VA) was measured in 50 myopic children; contrast sensitivity (CS) was measured in 36 myopic children. For each test, four spectacle lenses were evaluated in a random order: single-vision lens (SVL), lens with concentric rings of highly aspherical lenslets (HAL), lens with concentric rings of slightly aspherical lenslets (SAL), and lens with honeycomb configuration of spherical lenslets (HC). The modulation transfer function (MTF) and MTF area (MTFa) were used to determine optical quality. All tests were performed monocularly on the right eye with full correction.Results: HAL and SAL had larger MTFa than HC. VA in lenses with lenslets was significantly reduced compared to SVL (all p < 0.01). The reduction in VA was worse with HC than with SAL (p = 0.02) and HAL (p = 0.03); no effect of lenslet asphericity was found (p > 0.05). VA changes induced by lenslets showed no correlation with spherical equivalent refraction (all p > 0.05) and were weakly positively associated with age for SAL (r = 0.36, p = 0.01) and HC (r = 0.31, p = 0.03), but not for HAL (p = 0.30). The area under the log contrast sensitivity function (AULCSF) decreased with HAL and HC (all p < 0.001) in all illumination levels, and AULCSF with HAL was higher than that with HC in a photopic condition (1.17 ± 0.10 vs. 1.10 ± 0.13, p = 0.0004). The presence of lenslets did not affect CS at 3 cycles per degree (cpd) (p = 0.80). At 6 to 18 cpd, CS was significantly reduced by HAL and HC (all p < 0.05), but not SAL (p > 0.05) compared to SVL. At high spatial frequencies (>12 cpd) both SAL and HAL reduced CS significantly less than HC (all p < 0.01).Conclusion: Short-term visual performance was minimally impaired by looking through the lenslet structure of myopia control spectacle lenses. Concentric rings with aspherical lenslets had a significantly lower impact on both VA and CS than honeycomb configuration with spherical lenslets.

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“…In addition to genetic susceptibility, several environmental factors, such as prolonged near work, increased digital screen time, and insufficient time spent outdoors, are recognized as important risk factors for myopic progression [1][2][3][4]. To control the epidemic of myopia, low-concentration atropine eye drops and specially designed contact lenses and spectacle lenses, such as defocus incorporated multiple segments (DIMS) lenses and aspherical lenslets, are recommended to reduce myopic progression and have now reached high levels of evidence [5][6][7].…”

Section: Introductionmentioning

confidence: 99%

Influence of coronavirus disease 2019 on myopic progression in children treated with low-concentration atropine

2021

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Purpose The outbreak of coronavirus disease 2019 (COVID-19) has caused many children to stay indoors. Increased near work and insufficient outdoor activities are considered important risk factors for myopic progression. This study aimed to compare the changes in myopic progression before and after COVID-19 in children treated with low-concentration atropine. Methods The records of 103 eyes of 103 children who were treated with low-concentration atropine eye drops were retrospectively reviewed. We classified children according to the concentration of atropine eye drops and children’s age. The beginning of the pre-COVID-19 period was set from January 2019 to May 2019, and the endpoint was set in March 2020. The beginning of the post-COVID-19 period was set in March 2020, and the endpoint was set from January 2021 to March 2021. We evaluated the questionnaires administered to children’s parents. Results A significant myopic progression was observed in the post-COVID-19 period compared to the pre-COVID-19 period in the 0.05% and 0.025% atropine groups (P < 0.001 and P = 0.020, respectively). For children aged 5 to 7 and 8 to 10 years, the axial elongations were significantly faster in the post-COVID-19 period than in the pre-COVID-19 period (P = 0.022 and P = 0.005, respectively). However, the rates of axial elongation and myopic progression were not significantly different between pre- and post-COVID-19 in children aged 11 to 15 years (P = 0.065 and P = 0.792, respectively). The average time spent using computers and smartphones and reading time were significantly increased, and the times of physical and outdoor activity were significantly decreased in the post-COVID-19 period compared to the pre-COVID-19 period. Conclusions The rates of myopic progression have increased substantially after the spread of COVID-19 with an increase in the home confinement of children. Therefore, it is necessary to control the environmental risk factors for myopia, even in children undergoing treatment for the inhibition of myopic progression.

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One-year myopia control efficacy of spectacle lenses with aspherical lenslets

Cited by 95 publications

References 33 publications

The impact of spectacle lenses for myopia control on visual functions

The impact of spectacle lenses for myopia control on visual functions

Influence of Lenslet Configuration on Short-Term Visual Performance in Myopia Control Spectacle Lenses

Influence of coronavirus disease 2019 on myopic progression in children treated with low-concentration atropine

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