One‐year outcome in first episode psychosis patients in the Swedish Parachute project

Abstract

It is possible to successfully treat FEP patients with fewer in-patient days and less neuroleptic medication than is usually recommended, when combined with intensive psychosocial treatment and support.

Treatment of Acute Psychosis Without Neuroleptics: Two-Year Outcomes From the Soteria Project

“…We regard this closure of inquiry as premature. Current Scandinavian projects involving inhome family crisis intervention, avoiding use of hospitals and neuroleptics, and providing continuity of teams and approach over an extended period have shown highly promising results for the treatment of patients with newly diagnosed psychosis (Lehtinen et al, 2000;Cullberg et al, 2002). The Scandinavian results, Ciompi's Soteria replication (Ciompi et al, 1992(Ciompi et al, , 1993, and the findings reported here indicate that, contrary to popular views, minimal use of antipsychotic medications combined with specially designed psychosocial intervention for patients newly identified with schizophrenia spectrum disorders is not harmful but appears to be advantageous.…”

Duration of untreated psychosis and negative symptoms — A systematic review and meta-analysis of individual patient data

“…A total of 402 papers were identified by the search strategy, from which we identified 28 non-overlapping first episode studies that met inclusion criteria (see Appendix 1) (Montague et al, 1989;Barnes et al, 2000;Craig et al, 2000;de Haan et al, 2000;Drake et al, 2000;Ho et al, 2000;Larsen et al, 2000;Black et al, 2001;Verdoux et al, 2001;Cullberg et al, 2002;Malla et al, 2003;Addington et al, 2004;Sim et al, 2004;Chen et al, 2005;Harris et al, 2005;Manchanda et al, 2005;Melle et al, 2005;Oosthuizen et al, 2005;Petersen et al, 2005;Wade et al, 2005;Clarke et al, 2006;Ucok et al, 2006;Wunderink et al, 2006;Crespo-Facorro et al, 2007;Malla et al, 2007;Vyas et al, 2007;Gorna et al, 2008;Yamazawa et al, 2008). The selected studies included a total of 3998 participants.…”

Terapia de grupo en primeros episodios psicóticos

“…Estos son, en cualquier caso, los mayores problemas que nos encontramos en casi todos los estudios a la hora de evaluar programas terapéuticos: las muestras suelen ser pequeñas a no ser que se engloben en proyectos conjuntos de ámbito nacional o regional y la randomización difícil dada la baja incidencia del trastorno, más aún en nuestro entorno donde no existen modelos comunes de intervención, en el caso de estudios de intervención precoz estas carencias son especialmente notables (17). Además compartimos con Cullberg et al (2002) las dudas éticas que supone randomizar a pacientes a un tratamiento intensivo frente a otro de baja intensidad (18). Sin embargo las grandes diferencias existentes en la evolución de ambos grupos hacen que nos cuestionemos que éstas se deban tan sólo al azar.…”