One-year outcomes in patients with COVID-19 and clinical heart failure or elevated NT-proBNP

Codon, J Caro; Merino, José Luís; Sánchez, Andrea Severo; Santana, B Rivero; Buño, Antonio; Rey, J.

doi:10.1016/j.rccl.2023.02.001

Cited by 1 publication

(1 citation statement)

References 5 publications

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“…Truong et al [ 26 ] reported low HRQoL in Vietnamese patients with chronic heart failure, evidenced by particularly low scores in role limitations due to physical health (median 0, IQR 0-25) and general health perceptions (median 25) on the SF-36 scale. In contrast, Caro-Cardon et al [ 27 ] examined post-COVID-19 heart failure outcomes, finding a 27.5% incidence of new heart failure episodes and a 17.6% mortality rate among patients with either clinical heart failure or elevated NT-proBNP. Despite the acute onset and severity of heart issues in the COVID-19 context, quality of life outcomes measured by KCCQ-12 showed no significant differences between these groups, indicating persistent challenges in heart failure management irrespective of the underlying cause or healthcare setting.…”

Section: Discussionmentioning

confidence: 99%

Evaluating the Health-Related Quality of Life in Patients with COPD and Chronic Heart Failure Post-Hospitalization after COVID-19 Using the EQ-5D and KCCQ Questionnaires

Sukosd,

Gadde,

Pravallika

et al. 2024

Diseases

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Chronic heart failure (CHF) and chronic obstructive pulmonary disease (COPD) frequently coexist, significantly impacting health-related quality of life (HRQoL). This study evaluated HRQoL in patients with CHF, COPD, or both, three months post-COVID-19 discharge using EQ-5D and KCCQ questionnaires to guide targeted healthcare interventions. We conducted a cross-sectional study at “Victor Babes” Hospital in Timisoara, enrolling 180 patients who had recovered from COVID-19 (60 in each group including CHF, COPD, and both conditions). HRQoL was assessed via EQ-5D and KCCQ. Significant disparities in HRQoL measures were noted across the groups. Patients with both CHF and COPD reported the worst outcomes, especially in terms of hospital stay lengths due to COVID-19 (11.63 days) and initial oxygen saturation levels (88.7%). HRQoL improvements from discharge to three months post-discharge were significant, with EQ-5D mobility scores improving notably across all groups (CHF and COPD: 2.87 to 2.34, p = 0.010). KCCQ results reflected substantial enhancements in physical limitation (CHF and COPD: 38.94 to 58.54, p = 0.001) and quality of life scores (CHF and COPD: 41.38 to 61.92, p = 0.0031). Regression analysis revealed that dual diagnosis (CHF and COPD) significantly impacted usual activities and quality of life (β = −0.252, p = 0.048; β = −0.448, p = 0.017), whereas the initial severity of COVID-19 was a significant predictor of worse HRQoL outcomes (β = −0.298, p = 0.037; β = −0.342, p = 0.024). The presence of both CHF and COPD in patients recovering from COVID-19 was associated with more severe HRQoL impairment compared with either condition alone. These findings emphasize the need for specialized, comprehensive post-COVID-19 recovery programs that address the complex interplay among chronic conditions to optimize patient outcomes and enhance quality of life.

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Section: Discussionmentioning

confidence: 99%