One-Year Quality of Life Trends in Early-Stage Lung Cancer Patients After Lobectomy

Abstract

Objective: Quality of Life (QoL) is an important predictor of patient's recovery and survival in lung cancer patients. The aim of the present study is to identify 1-year trends of lung cancer patients' QoL after robot-assisted or traditional lobectomy and investigate whether clinical (e.g., pre-surgery QoL, type of surgery, and perioperative complications) and sociodemographic variables (e.g., age) may predict these trends.Methods: An Italian sample of 176 lung cancer patients undergoing lobectomy completed the European Organization for Research and Treatment of Cancer (EORTC) Quality of Life Questionnaire—Core 30 (QLQ-C30) at the pre-hospitalization (t0), 30 days (t1), 4 months (t2), 8 months (t3), and 12 months (t4) after surgery. Sociodemographic and clinical characteristics (age, gender, perioperative complications, and type of surgery) were also collected. The individual change over time of the 15 dimensions of the EORTC QLQ-C30 and the effects of pre-surgery scores of QoL dimensions, type of surgery, perioperative complications, and age on patients' QoL after surgery were studied with the individual growth curve (IGC) models.Results: Patients had a good recovery after lobectomy: functioning subscales improved over time, while most of the symptoms became less severe over the care process. Perioperative complications, type of surgery, pre-surgery status, and age significantly affected these trends, thus becoming predictors of patients' QoL.Conclusion: This study highlights different 1-year trends of lung cancer patients' QoL. The measurement of pre- and post-surgery QoL and its clinical and sociodemographic covariables would be necessary to better investigate patients' care process and implement personalized medicine in lung cancer hospital divisions.

The Importance of Social Support, Optimism and Resilience on the Quality of Life of Cancer Patients

“…Many patients who overcame cancer find it difficult to go back to a new way of life, which can also impact their quality of life ( Götze et al, 2015 ). Patients’ quality of life is affected by specific factors related to the medical process, such as the specific treatment administered ( Marzorati et al, 2020 ), the location or type of cancer and the secondary effects derived from each treatment ( Gargantini and Martín Casari, 2019 ; Nilsen et al, 2021 ), as well as sociodemographic factors such as patients’ gender. Males tend to perceive higher quality of life than females ( Ayalon and Bachner, 2019 ).…”

Quality of Life After Stereotactic Body Radiation Therapy or Surgery for Early-Stage NSCLC: A Systematic Review

“…A total of 25 prospective studies met the inclusion criteria and were included in this study for analysis. 6 , 13 , 14 , 15 , 16 , 17 , 18 , 19 , 20 , 21 , 22 , 23 , 24 , 25 , 26 , 27 , 28 , 29 , 30 , 31 , 32 , 33 , 34 , 35 , 36 Publication years ranged from 2003 to 2022. The PRISM decision tree is illustrated in Figure 1 .…”

“…Table 2 summarizes the characteristics and outcomes for studies evaluating QOL after surgery alone. 13 , 14 , 20 , 23 , 29 , 30 , 31 , 33 , 35 All patients in the nine studies were diagnosed with having stage I or II NSCLC. The median number of patients was 173 and median age of patients was 67 years.…”

Toxicities and Quality of Life during Cancer Treatment in Advanced Solid Tumors

“…Several studies have demonstrated that patients experiencing severe adverse events during cancer treatment had a higher risk of treatment interruption, discontinuation, and death [32][33][34]. In addition, these toxicities can affect patients' quality of life and increase healthcare costs [35][36][37]. Therefore, managing toxicity is an important aspect of cancer treatment to improve patient outcomes.…”