2002
DOI: 10.1007/s00134-001-1188-z
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One-year survival and neurological outcome after pediatric cardiopulmonary resuscitation

Abstract: Independent determinants of long-term survival of pediatric resuscitation are location of arrest, underlying cause, and duration of CPR. Long-term survivors have little or no change in neurological status.

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Cited by 45 publications
(25 citation statements)
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“…It is important to point out that this study, as well as other studies, show that prolonged CPR (>20 min) can be compatible with survival. 7,8,17 On univariate analysis, we found an association between 2-year mortality and the number of doses of epinephrine and bicarbonate; however, this was no longer significant on multiple regression analysis. Stronger associations were suggested in largely non-cardiac pediatric patients, in which the number of doses of epinephrine and bicarbonate were higher in non-survivors.…”
Section: Discussionmentioning
confidence: 47%
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“…It is important to point out that this study, as well as other studies, show that prolonged CPR (>20 min) can be compatible with survival. 7,8,17 On univariate analysis, we found an association between 2-year mortality and the number of doses of epinephrine and bicarbonate; however, this was no longer significant on multiple regression analysis. Stronger associations were suggested in largely non-cardiac pediatric patients, in which the number of doses of epinephrine and bicarbonate were higher in non-survivors.…”
Section: Discussionmentioning
confidence: 47%
“…Several groups however, have reported pediatric CPR outcomes in pediatric intensive care unit (PICU) [5][6][7] or in out/inpatients. [8][9][10][11] One-year survival from PICU resuscitations that included in part a wide age range of cardiac patients varied from 23% 5 to 54%, 8 with mild to no change in long term functional and neurologic status. 5,6,8 Comparatively, 1-year survival in out/inpatients having CPR has been reported at 33%, 11 with one study documenting that the majority of children demonstrated low adaptive behavior, achievement and neuropsychologic measures.…”
Section: Introductionmentioning
confidence: 99%
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“…However, many studies were single-center studies, focused on out-of-hospital arrests (or both IHCA and out-of-hospital arrests), or used retrospectively collected data. 15,24,30 Inclusion of adults, smaller sample sizes, and inconsistent definitions also made it difficult to quantify the true impact of CPR duration and patient illness category in these studies. However, our study used prospectively collected data from multiple centers using the Utstein guidelines for uniform data reporting, carefully minimizing information bias, observer bias, and surveillance bias.…”
Section: Discussionmentioning
confidence: 99%
“…In this tiny infant (body weight 2.95 kg) with extensive thromboses in major venous vessels, neither peritoneal nor haemodialysis was an immediately available option. The key to the successful resuscitation of this infant was (1) the monitoring in place including arterial access [3], (2) the immediate start of conventional measures to shift potassium from the extracellular into the intracellular compartment [2] and (3) the data-guided (arterial blood analysis and blood pressure) advanced cardiac life support performed by highly skilled staff. This child possibly survived under conventional measures because the acutely infused amounts of potassium had not yet been distributed into the extravascular space, unlike the more gradual onset of potassium intoxication from enteral sources.…”
mentioning
confidence: 99%