“…Advances in the acquisition and segmentation of high-throughput volume electron microscopy (VEM) create larger data sets (Kornfeld and Denk, 2018) that stress data management tools due to the volume of data, the need to support proofreading as well as automated, high-throughput batch operations, and the sharing and integration of results from different research groups. While many data distribution systems focus on large numbers of relatively small datasets or file-based distribution (Dutka et al, 2015; Viljoen et al, 2016), VEM reconstructions are not easily distributed and usable to researchers through file distribution. For teravoxel to petavoxel datasets, centralized data services can provide low latency access to areas of interest without requiring the download of much larger volumes of data (Saalfeld et al, 2009; Burns et al, 2013; Haehn et al, 2017; Kleissas et al, 2017).…”