Ongoing Positive Effect of Platelet-Rich Plasma Versus Corticosteroid Injection in Lateral Epicondylitis

Abstract

Background: Platelet-rich plasma (PRP) has been shown to be a general stimulation for repair and 1-year results showed promising success percentages.

A randomized study of autologous conditioned plasma and steroid injections in the treatment of lateral epicondylitis

“…In addition, a quicker therapeutic effect was noted for steroid injections compared to platelet-rich plasma, although the effect was not as long lasting. These same group evaluated the same group of patients for two years from the administration of injections, achieving better results in the group treated with platelet-rich plasma preparations when returning to baseline than patients treated with steroids [7]. A similar conclusion regarding the short-term beneficial effects of steroid therapy may be found in Coombes et al [8].…”

“…The literature proposes several options for treating lateral epicondylitis (LE), including activity modification, physical therapy, operative treatment, pharmacotherapy, of the injection of botulinum toxin, steroids, platelet rich plasma (PRP), autologous conditioned plasma (ACP) [2][3][4][5][6][7][8][9][10][11][12][13]. The origins of ACP and PRP usage were connected with dentistry and plastic surgery, and then later in Orthopedics and especially in sports medicine [14,15].…”

Platelet-Rich Plasma Therapies in Lateral Epicondylitis: Are we Asking the Right Questions?

“…Significant differences have been demonstrated between the White Blood Cell (WBC) and growth factor levels produced using various commercial PRP separation systems [13,14]. Studies have differed in the quantities of PRP injected (ranging from 1.5 mL to 3.5 mL), either alone or in combination with variable amounts of local anaesthetic and/or epinephrine [15][16][17][18][19]. The number of injections given and time intervals between injections also varies between studies.…”

Results of Operative Treatment of Lateral Epicondylitis

“…Ключевые слова: эпикондилит плечевой кости, оперативное лечение, отдаленные результаты. не воспалительный, а дегенеративно-дистрофический процесс [6]. Среди иностранных авторов довольно часто используют термин tennis elbow -«локоть теннисиста», отмечая, что значительное количество игроков в большой теннис страдают этим заболеванием [4].…”