Ongoing Quality Assessment/Improvement in Clinical IVF

Bormann, Charles L.; Racowsky, Catherine

doi:10.1007/978-1-4419-9848-4_15

Cited by 3 publications

(1 citation statement)

References 42 publications

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“…No data is available on potential harmful or discomforting effects in humans, but these two studies in animals do not show any evidence for this. As stated by Borman and Racowsky (2012): 'In the field of assisted reproduction, there is no room for mistakes'. The Human Fertilisation and Embryology Authority considers an embryo mix-up as a grade A incident (the most serious incident).…”

Section: Discussionmentioning

confidence: 99%

Traceability of human sperm samples by direct tagging with polysilicon microbarcodes

Novo

Mora-Espí

Gómez-Martínez

et al. 2015

Reproductive BioMedicine Online

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The increasing number of patients undergoing assisted reproductive technology (ART) treatments and of cycles performed in fertility centres has led to some traceability errors. Although the incidence of mismatching errors is extremely low, any error is unacceptable, therefore different strategies have been developed to further minimize these errors, such as manual double-witnessing or electronic witnessing systems. More recently, our group developed a direct tagging method consisting of attaching microbarcodes directly to the zona pellucida of human oocytes/embryos. Here, this method is taken a step further by using these microbarcodes to tag human semen samples, demonstrating that the barcodes are not toxic and do not interfere in the selection of motile spermatozoa nor in the cryopreservation of the sperm samples. In addition, when this tagging system was applied to an animal model (rabbit), pregnancy rate and kitten viability were not affected.

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Section: Discussionmentioning

confidence: 99%

Traceability of human sperm samples by direct tagging with polysilicon microbarcodes

Novo

Mora-Espí

Gómez-Martínez

et al. 2015

Reproductive BioMedicine Online

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Electronic whiteboard implementation as a quality management tool optimizes IVF laboratory standardization and improves clinical outcomes

Romanski

Thomas

Patel

et al. 2020

J Assist Reprod Genet

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Purpose To test whether an electronic whiteboard in the IVF laboratory increases the likelihood that critical evaluation procedures are performed within optimum pre-set time ranges. Methods A retrospective cohort study of oocyte retrievals in our IVF clinic between 06/01/2012 and 05/31/2018 was included. The electronic whiteboard was introduced on 04/06/2014. Prior to implementation, embryologists strived to adhere to the set evaluation times without a formal guide. The primary outcomes were the proportion of embryologist evaluations performed in optimum time ranges and the proportion of usable embryos per patient. Results A total of 4645 retrievals met inclusion criteria. Implementation of the whiteboard was associated with (1) an increase in the proportion of fertilization checks performed within the optimum time range for ICSI cycles (+ 5.1%, RR = 1.06, CI = 1.02-1.10); (2) an increase in the proportion of day 3 evaluations performed within the optimum time range, whether assisted hatching was performed (+ 23.6%, RR = 1.48, CI = 1.36-1.60) or not (+ 13.8%, RR = 1.23, CI = 1.12-1.35); and (3) an increase in the proportion of day 5 evaluations within the optimum time range (+ 15.5%, RR = 1.23, CI = 1.12-1.35). Additionally, the mean number of usable embryos per patient increased from 2.8 to 4.5 after the whiteboard was implemented (RR = 1.25, CI = 1.19-1.31). Conclusion The use of an electronic whiteboard that posts optimum times for performing critical procedures significantly increases the proportion of evaluations that occur within these ranges. Such improved standardization led to positive downstream effects on the number of usable embryos per patient. We suggest that electronic whiteboard implementation driven by real-time data collection should be considered in all IVF laboratories.

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Quality Management: Maintaining a Stable IVF Laboratory

Patel¹,

Racowsky²

2018

Encyclopedia of Reproduction

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Ongoing Quality Assessment/Improvement in Clinical IVF

Cited by 3 publications

References 42 publications

Traceability of human sperm samples by direct tagging with polysilicon microbarcodes

Traceability of human sperm samples by direct tagging with polysilicon microbarcodes

Electronic whiteboard implementation as a quality management tool optimizes IVF laboratory standardization and improves clinical outcomes

Quality Management: Maintaining a Stable IVF Laboratory

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