This paper discusses the guided and automatic control configuration selection in large scale complex systems. Due to the trend of increasesd level of automation and connectedness which is promoted by the Industry 4.0 strategy and supported by technologies relating to cyber-physical systems and the industrial internet of things, selecting appropriate control strategies becomes increasingly important and complex. This is especially important as a control strategies will limit the achievable performance of the process system, and there are trade-offs between complexity of the control strategies, achievable performance, vulnerability and maintainability. The paper reviews the state of the art of methodologies that support the practitioners in taking decisions on control strategies, where two main approaches are considered, the guided one and a fully automatic one. It is shown how both approached can be conducted and examples are used to clarify the selection process.