Onset and long-term duration of immunity provided by a single vaccination with recombinant a Marek’s disease virus with REV-LTR insertion
Jun Dai,
Cuiping Song,
Lei Tan
et al.
Abstract:Marek’s Disease (MD), caused by Marek’s disease virus (MDV), is a highly contagious lymphoproliferative disease in poultry. Despite the fact that MD has been effectively controlled by vaccines, the virulence of field isolates of MDV has continued to evolve, becoming more virulent under the immune pressure of vaccines. Our previous research has confirmed that the recombinant rMDV strain with REV-LTR insertion can be used as a live attenuated vaccine candidate. The aim of this research was to evaluate the onset … Show more
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