Onychomadesis during bullous pemphigoid

Benmously-Mlika, Rym; Hammami-Ghorbel, Houda; Mokhtar, I.

doi:10.1016/j.jaad.2013.07.011

Cited by 8 publications

(21 citation statements)

References 5 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…11 In BP, paronychia, onychorrhexis, Beau's lines, onychomadesis, subungual hyperkeratosis, longitudinal melanonychia, pterygium, dystrophy, onycholysis, and nail loss have been previously reported. 10,[13][14][15]17,[19][20][21][22][27][28][29][30] In a study of 12 patients with BP, the most frequent nail alteration was paronychia followed by onychorrhexis and Beau's lines. 10 We found paronychia to be the fourth most common finding in patients with BP following periungual bullae, onycholysis, and ridging (onychorrhexis) (Table S1).…”

Section: Discussionmentioning

confidence: 99%

“…13 Few cases with paronychia, nail dystrophy, nail loss, ridging, onychomadesis, pterygium, onychorrhexis, and Beau's lines have been reported as yet. 10,12,[14][15][16][17] The presence of nail abnormalities may be a sign of more severe disease as suggested for other blistering diseases such as pemphigus vulgaris. 10,12,15,18 The nail lesions typically disappear once the overall disease course has been controlled, but in some patients, permanent changes and scarring may occur.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Nail abnormalities in subepidermal blistering diseases: a cross‐sectional study

et al. 2023

View full text Add to dashboard Cite

Background Nail involvement in subepidermal autoimmune blistering diseases (SEABD) is not common. Although these changes can be transient, permanent changes can also occur. This study addresses nail involvement manifestations and their associated factors in patients with SEABD.Methods From March 2020 to March 2021, we enrolled 56 patients with SEABD who were being examined at a tertiary skin hospital and checked their nail changes. We investigated the association between the SEABD subtypes and treatments that patients were receiving and the nail abnormalities. Additional factors including age, gender, duration since diagnosis, presence of mucosal involvement, and anti-bp230 and anti-bp180 IgG antibody quantitative levels (in those patients with bullous pemphigoid) were analyzed. ResultsThe most common nail abnormalities were ridging, onycholysis, and onychoschizia. We observed a lower prevalence of onycholysis in EBA, a lower prevalence of periungual bullae in MMP, and a higher prevalence of scarring loss in EBA. Rituximab and dapsone were effective in preventing onycholysis as well as prednisolone in preventing subungual hematoma. Multiple lesions were found to be more common in the foot digits including great toes, probably because of higher exposure to trauma.Conclusions In summary, in patients with SEABD and concomitant nail involvement, the underlying disease control, proper treatment, and avoidance of trauma may be helpful.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Nail abnormalities in subepidermal blistering diseases: a cross‐sectional study

et al. 2023

View full text Add to dashboard Cite

show abstract

“…The nail apparatus is very rarely affected during BP. The most common nail alterations reported in literature data are nail loss [1][2][3][4], onychomadesis [5], pterygium [6], and paronychia.…”

Section: Discussion/conclusionmentioning

confidence: 99%

Uncommon Nail Involvement during Bullous Pemphigoid

Zaouak

Gara

Fenniche

2021

Skin Appendage Disord

View full text Add to dashboard Cite

Bullous pemphigoid (BP) is the most frequent autoimmune blistering disorder. The immune reaction targets BP180 and BP230 antigens, 2 components of junctional adhesion complexes at the basement membrane zone. Clinical aspect includes multiple tense bullae on urticarial plaques of the skin. Although the nail apparatus may be affected by the immune process, nail changes have been rarely reported during BP. We report a case of a 72-year-old woman diagnosed with BP who subsequently developed a secondary nail loss of the 2 thumbs and the left middle finger. Also, she presented onycholysis of the fourth left finger with the aspect of roller-coaster of the proximal border at dermoscopy. Steroid therapy at high doses was ineffective and the nail atrophy was permanent.

show abstract

“…One report described nail dystrophy and ptergyium formation in a patient with MMP [3]. Onychomadesis was also reported in a patient with BP [13].…”

Section: Discussionmentioning

confidence: 99%

Mucous membrane pemphigoid-associated paronychia with onychomadesis

Alkeraye

Alsukait

2019

BMC Dermatol

View full text Add to dashboard Cite

BackgroundMucous membrane pemphigoid (MMP) is an autoimmune blistering disease that is notoriously difficult to treat. Nail involvement in MMP is rare.Case presentationWe report on a 58 years old man with severe MMP who presented with onychomadesis.ConclusionTo our knowledge, mucous membrane pemphigoid associated paronychia and onychomadesis have not been reported before. We believe it is important for dermatologists to be aware of this entity.

show abstract

Onychomadesis during bullous pemphigoid

Cited by 8 publications

References 5 publications

Nail abnormalities in subepidermal blistering diseases: a cross‐sectional study

Nail abnormalities in subepidermal blistering diseases: a cross‐sectional study

Uncommon Nail Involvement during Bullous Pemphigoid

Mucous membrane pemphigoid-associated paronychia with onychomadesis

Contact Info

Product

Resources

About