Oocyte and embryo cryopreservation in assisted reproductive technology: past achievements and current challenges

Casciani, Valentina; Monseur, Brent; Cimadomo, Danilo; Alvero, Ruben J.; Rienzi, Laura

doi:10.1016/j.fertnstert.2023.06.005

Cited by 12 publications

(2 citation statements)

References 181 publications

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“…( 4) Alternatives to cryopreservation (use of fresh donor tissue when available). Furthermore, disposition of the frozen tissue in the case of the lack of continued wish for procreation [10], death or divorce or dissolution of a partnership, nonpayment of storage fees, and loss of contact with the person(s) should be covered in the consent form [76][77][78].…”

Section: The Importance Of Informed Consentmentioning

confidence: 99%

Fertility Preservation Options for Transgender Patients: An Overview

Mainland,

Ohl,

Assaly

et al. 2023

Uro

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Fertility preservation technologies have existed for decades, and the field is rapidly advancing; limited data exist regarding the use of these technologies by transgender patients. Many options are available for transgender patients who wish to preserve fertility before transitioning. These options include the cryopreservation of gametes, embryos, or ovarian tissue. Currently, ejaculated, or testicular sperm, immature oocytes, and ovarian tissue can be preserved for later use, but no such use option exists for immature testicular tissue. Many financial, sociological, and legal barriers and a lack of awareness among physicians and patients also hinders the utilization of these fertility preservation services. While options are abundant, usage rates are relatively low. The initial data regarding the successful use of preserved tissues appears promising, with birth rates not dissimilar to non-transgender patients. Further investigations into this area are needed. In addition, counseling regarding fertility preservation options should become a significant part of the provider-patient conversation before transitioning therapies.

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Section: The Importance Of Informed Consentmentioning

confidence: 99%

Fertility Preservation Options for Transgender Patients: An Overview

Mainland,

Ohl,

Assaly

et al. 2023

Uro

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“…The application of assisted reproductive technologies such as IVF and embryo transfer in clinical practice has greatly improved the live birth rate and clinical pregnancy rate. [27,28] The rate of IVF births has significantly increased, accounting for approximately 1% to 3% of all newborns. With the help of ART technology, many patients have realized their dreams of giving birth.…”

Section: Introductionmentioning

confidence: 99%

Cohort differences between preschool development of in vitro fertilization and naturally conceived infants

Guo,

Wang,

Yang

et al. 2024

Medicine

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To explore the differential cohort situation between preschool development of in vitro fertilization (IVF) and naturally conceived infants. From April 2014 to June 2022, 60 preschool IVFs were selected as the research subjects for follow-up at the pediatric health clinic of hospital’s prevention and health department. They were set as the experimental group (Group S), and 60 naturally conceived infants of the same age were selected as the control group (Group Z). Data from both groups were collected through telephone follow-up and other methods. No significant difference showed between the 2 groups in age specific height, age specific weight, Gesell developmental score, Denver developmental screening test screening results, intellectual development index, and motor development index (P > .05). The influence of birth environment factors such as family background and maternal education level on children’s height and weight was not significant (P > .05), while maternal education level had a significant impact on children’s intellectual development index (P < .05). No significant difference showed in the development of preschool children in IVF compared to naturally conceived children, and the level of parental education has a significant impact on children’s mental and motor development.

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Molecular mechanisms of natural antifreeze phenomena and their application in cryopreservation

Shi,

Zang,

Liu

et al. 2024

Biotech & Bioengineering

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Cryopreservation presents a critical challenge due to cryo‐damage, such as crystallization and osmotic imbalances that compromise the integrity of biological tissues and cells. In contrast, various organisms in nature exhibit remarkable freezing tolerance, leveraging complex molecular mechanisms to survive extreme cold. This review explores the adaptive strategies of freeze‐tolerant species, including the regulation of specific genes, proteins, and metabolic pathways, to enhance survival in low‐temperature environments. We then discuss recent advancements in cryopreservation technologies that aim to mimic these natural phenomena to preserve cellular and tissue integrity. Special focus is given to the roles of glucose metabolism, microRNA expression, and cryoprotective protein modulation in improving cryopreservation outcomes. The insights gained from studying natural antifreeze mechanisms offer promising directions for advancing cryopreservation techniques, with potential applications in medical, agricultural, and conservation fields. Future research should aim to further elucidate these molecular mechanisms to develop more effective and reliable cryopreservation methods.

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Oocyte and embryo cryopreservation in assisted reproductive technology: past achievements and current challenges

Cited by 12 publications

References 181 publications

Fertility Preservation Options for Transgender Patients: An Overview

Fertility Preservation Options for Transgender Patients: An Overview

Cohort differences between preschool development of in vitro fertilization and naturally conceived infants

Molecular mechanisms of natural antifreeze phenomena and their application in cryopreservation

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