[OP.6C.01] New Epidemiologic National Representative Survey

PurposeThis study was performed to elucidate the level of adherence to antihypertensive treatment in adult subjects attending a family medicine clinic in a city in central Romania.Patients and methodsA cross-sectional, retrospective study was performed on a cohort of hypertensive adults. A total of 525 participants were selected from 1,714 adults attending a single urban family medicine practice. Assessment of adherence to therapy was performed by a chart review of prescription and clinical records over a 4-year study period.ResultsThe results showed that 69.8% of the patients had high adherence (>80% with therapy); 20.3% had medium adherence (20%–79%); and 9.9% had low adherence (<20%). A positive association was found (p = 0.01) between low adherence and male gender. A significant positive association (p = 0.02) was found between total cardiovascular risk and level of adherence. We found that 54.7% of the high adherence subjects had well-controlled blood pressure, and chronic kidney disease was associated with high adherence to therapy (p = 0.03). Antihypertensive regimens administered as fixed-dose combinations were positively associated with high adherence (p = 0.001). Subjects who had their antihypertensive regimen adjusted to a new drug class during the study period showed enhanced adherence compared to subjects treated with an unchanged regimen (p = 0.001).ConclusionThis is the first published study assessing adherence to antihypertensive therapy in family medicine practice in Romania. It presented data derived from a primarily urban setting and targeted a geographical area where the prevalence of hypertension has increased continuously. Female gender, age, presence of cardiovascular risk factors, defined cardiovascular disease, chronic renal impairment, and good control of hypertension were positively associated with high adherence. The results provide insights to guide further strategies to improve adherence and indirect methods for blood pressure management strategies.

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“…It is estimated that by 2020 the prevalence of HTN will increase to 44% with treatment control of 36.6%. 3 , 4 …”

Section: Introductionmentioning

confidence: 99%

Treatment adherence among adult hypertensive patients: a cross-sectional retrospective study in primary care in Romania

Ţilea

Petra

Voidăzan

et al. 2018

PPA

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“…Most patients initially had stage 3 hypertension, and only 41.52% reported normalized blood pressure after treatment, which is in accordance with findings from the SEPHAR III study. 6 , 7 The low rate of therapeutic response cannot be ascribed to pharmacotherapy regimens because almost half of the patients (46.71%) used at least two drugs and 21.1% received antihypertensive triple therapy. Most patients in our study did not know the doses of drugs in their therapeutic regimens.…”

Section: Discussionmentioning

confidence: 99%

“…Hypertension and its complications can adversely affect patients’ daily activities and lead to dissatisfaction, depression, and irritability. 6 , 7 …”

Section: Introductionmentioning

confidence: 99%

“…Hypertension and its complications can adversely affect patients' daily activities and lead to dissatisfaction, depression, and irritability. 6,7 Given the chronic nature of essential hypertension and its association with multiple diseases, it is important to establish the factors contributing to its high prevalence in Romania. To this end, in this study, we used a specially designed questionnaire to identify factors affecting patients' shortand long-term adherence to therapy and QoL.…”

Section: Introductionmentioning

confidence: 99%

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Factors Influencing Adherence to Treatment and Quality of Life for a Group of Patients with Essential Hypertension in Romania

Suciu

Voicu

et al. 2021

PPA

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Purpose Romania has a high prevalence of hypertension (45.1% in 2016). Whether this is attributable to a low rate of treatment adherence—which can aggravate the pathology and reduce patients’ quality of life (QoL)—is unknown. To address this point, the present study investigated the factors that influence short- and long-term adherence and QoL in patients with arterial hypertension using a specially designed questionnaire. Patients and Methods The study enrolled 289 patients at different stages of hypertension with or without comorbidities. The diagnosis of hypertension was established by the cardiologist, and treatment regimens were communicated by patients to the clinical pharmacist who administered the questionnaire, which comprised 7 domains with variable numbers of items. Results The majority of surveyed patients (57.43%) considered that their capacity for effort was decreased because of their hypertension, with 65.05% reporting that they were affected by symptoms associated with high blood pressure (eg, headache and dizziness). Most patients (71.28%) understood the consequences of discontinuing their medication and the severe complications of hypertension, and 69.55% indicated that they would not stop treatment if they experienced side effects. For 53.28% of patients, social activity was significantly affected by their condition. Only 47.05% of patients underwent regular mandatory medical examinations and 55.36% periodically monitored their blood pressure at home. A regression analysis revealed correlations between specific questionnaire items and patient characteristics. Conclusion Nonpharmacologic factors that were shown to influence patients’ adherence to treatment and QoL included the level of health education and knowledge of disease complications, self-monitoring of hypertension, and consultation with medical and pharmaceutical healthcare providers regarding hypertension and its treatment.

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“…Cardiovascular diseases remain a major health problem on a global scale, accounting for the majority (i.e. 60%) of deaths in Romania 1 . Of these, arterial hypertension (HTN) is the most common, with an estimated prevalence among the adult population of 45.1% according to the SEPHAR III study 1 .…”

Section: Introductionmentioning

confidence: 99%

Arterial hypertension and aortic diseases

Tîrziu

2020

Arch Balk Med Union

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[OP.6C.01] New Epidemiologic National Representative Survey

Cited by 4 publications

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Treatment adherence among adult hypertensive patients: a cross-sectional retrospective study in primary care in Romania

Treatment adherence among adult hypertensive patients: a cross-sectional retrospective study in primary care in Romania

Factors Influencing Adherence to Treatment and Quality of Life for a Group of Patients with Essential Hypertension in Romania

Arterial hypertension and aortic diseases

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