OP16.07: How to measure size of tubal ectopic pregnancy on ultrasound scan?

Rajah, K.; Goodhart, Venetia; Kriedt, Kathiuska; Amin, T.; Jauniaux, Eric

doi:10.1002/uog.19540

Cited by 2 publications

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“…Pregnancies were dated according to the last menstrual period (LMP). Other measurements obtained during the scan and collected for the study were presence of hemoperitoneum (nil/mild/significant), the size (mean diameter) and morphology of TEP (solid/presence of gestational sac/presence of yolk sac/presence of embryo/presence of embryonic cardiac activity) as previously described 22 . Our selection criteria for expectant management have been previously published and they included:…”

Section: Methodsmentioning

confidence: 99%

Evaluation of maternal serum biomarkers in predicting outcome of successful expectant management of tubal ectopic pregnancies

Memtsa

Jauniaux

Gulbis

2020

European Journal of Obstetrics & Gynecology and Reproductiv

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Objective: To assess the value of multiple serum biomarkers for the prediction of successful outcome of expectant management in women with tubal ectopic pregnancy (TEP). Study design:Women with a conclusive ultrasound diagnosis of TEP had a blood test to measure β-human chorionic gonadotropin (β-hCG), progesterone, inhibin A, activin A and high sensitivity C-reactive protein (hsCRP) at the initial visit. Women presenting with pain, serum b-hCG ≥ 1,500 IU, evidence of a live ectopic pregnancy or a significant haemoperitoneum were advised to have emergency surgery. Women eligible for expectant management were followed-up prospectively until serum β-hCG declined to non-pregnant level or surgical treatment was required.Results: A total of 93 women with a TEP were included in the final cohort.Emergency surgery was carried out in 42/93 (45%) of women whilst 51/93 (55%) were managed expectantly. Of the latter group, 42/51 (82%) had successful expectant management and 9/51(18%) required surgical procedure after a period of follow up. On multi-variable analysis, only higher values of serum b-hCG and progesterone at the initial visit were associated with a lower chance of successful expectant management of TEP. A one-unit increase in either variable on the log-scale was associated with an approximate 20-fold reduction in the odds of a successful outcome. Conclusion(s):Serum β-hCG and progesterone were significantly lower in women who had successful expectant management of TEP. Other biomarkers under consideration were not significantly different in women with successful and failed expectant management.

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Section: Methodsmentioning

confidence: 99%

Evaluation of maternal serum biomarkers in predicting outcome of successful expectant management of tubal ectopic pregnancies

Memtsa

Jauniaux

Gulbis

2020

European Journal of Obstetrics & Gynecology and Reproductiv

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“…Moderate hemoperitoneum was diagnosed on TVS examination when there were visible blood clots within the POD and severe hemoperitoneum was diagnosed when blood and clots were present both in the POD and in the vesicouterine space 13 . We used the term significant to describe hemoperitoneum which was severe enough to result in the formation of blood clots within the peritoneal cavity.…”

Section: Methodsmentioning

confidence: 99%

Hemoperitoneum as a precursor of deep pelvic endometriosis: prospective cohort study

Bean

Cutner

Sarıdoğan

et al. 2019

Ultrasound in Obstet & Gyne

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To determine whether significant hemoperitoneum could be a precursor of deep pelvic endometriosis Methods This was a prospective observational cohort study which was carried out in a dedicated gynecological diagnostic unit over a period of 18 months. We included consecutive pre-menopausal, non-pregnant women who attended with severe acute lower abdominal pain and underwent a pelvic ultrasound examination. Women were triaged for surgical or conservative management depending on the cause of pain and severity of their symptoms. Those who were selected for conservative management were invited for follow up ultrasound scans. The main outcome measure was evidence of newly developed deep endometriosis at follow up. Results This article is protected by copyright. All rights reserved. One hundred and eighteen non-pregnant women attended with severe acute lower abdominal pain, 20 of whom had emergency surgery. Seventeen women with past history of endometriosis or evidence of endometriosis on the initial scan were excluded from the study. Conservative management was employed in 81 women, eight of whom had evidence of significant hemoperitoneum at presentation. A total of 35 women attended for all their follow up ultrasound scans. At the completion of follow up 4/6 (67%, 95% CI 22-96)] women who initially presented with significant intraabdominal bleeding had developed new evidence of DE compared to 1/29 (3%, 95% CI 0-18) of those without hemoperitoneum. (RR 19.3 (95% CI 3-144) (p=<0.001). Conclusion In some women, the presence of significant hemoperitoneum that is managed conservatively precedes the development of deep endometriosis (DE).

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OP16.07: How to measure size of tubal ectopic pregnancy on ultrasound scan?

Cited by 2 publications

References 0 publications

Evaluation of maternal serum biomarkers in predicting outcome of successful expectant management of tubal ectopic pregnancies

Evaluation of maternal serum biomarkers in predicting outcome of successful expectant management of tubal ectopic pregnancies

Hemoperitoneum as a precursor of deep pelvic endometriosis: prospective cohort study

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