This chapter explores some of the challenges and opportunities for expansion of open, distance, and digital education in the global south. The discussion begins by defining the terms as used in the chapter and explains why such approaches are of relevance to the diverse countries involved. The chapter then provides some current examples of open, distance, and digital education provision and how some of these practices have been adapted in response to external factors such as climate, financial, and pandemic crises. The chapter then discusses the challenges and opportunities indicated both by current practice and by current research into issues such as open pedagogy, technology-enabled learning, and educational financing. The chapter then makes an argument for the development of more resilient, future-directed education provision, drawing heavily on the experience of the Commonwealth of Learning in its efforts to support sustainable development through learning.