Open flap debridement of peri‐implantitis with or without adjunctive systemic antibiotics: A randomized clinical trial

Abstract

Surgical treatment of peri-implantitis with adjunctive systemic azithromycin did not provide 1-year clinical benefits in comparison with those only receiving open flap debridement.

One‐year results of a nonsurgical treatment protocol for peri‐implantitis. A retrospective case series

“…Still, the outcomes observed in this study concerning pocket depth reduction (2.19 mm) and mean bone gain (0.91 mm) are a little higher than the ones reported by Hallström, Persson, Lindgren, and Renvert (2017) after an open flap debridement approach. They achieved a mean probing depth reduction of 1.7 mm in the test group and of 1.6 mm in the control group, and a mean bone gain of 0.6 mm and 0.4 mm in the test and control groups, respectively.…”

Regenerative surgical treatment of peri‐implantitis using either a collagen membrane or concentrated growth factor: A 12‐month randomized clinical trial

“…These findings are in accordance with the findings of previous studies. 7,8,32,33 To the best of our knowledge, there is no human study in literature for a direct comparison of the results of the CGF group. Therefore, this is the first clinical study evaluating the additional use of CGF as a resorbable membrane compared with the use of CM with a bonegrafting material for the reconstruction of PBD.…”

“…[3][4][5][6][7][8] Recent systematic reviews of clinical trials have reported that regenerative surgical treatment (RST) of peri-implantitis has been shown to result in improvements in probing depth (PD) reduction, BOP and radiographic evidence of defect fill (DF). [3][4][5][6][7][8] Recent systematic reviews of clinical trials have reported that regenerative surgical treatment (RST) of peri-implantitis has been shown to result in improvements in probing depth (PD) reduction, BOP and radiographic evidence of defect fill (DF).…”

“…surgical therapies with open flap debridement procedures, resective or regenerative approaches have been documented to achieve variable success. [3][4][5][6][7][8] Recent systematic reviews of clinical trials have reported that regenerative surgical treatment (RST) of peri-implantitis has been shown to result in improvements in probing depth (PD) reduction, BOP and radiographic evidence of defect fill (DF). [9][10][11][12] Barrier membranes are used in regenerative approaches to stabilize the graft and to prevent epithelial ingrowth and long junctional epithelium formation from the PBD, providing the population of bone cells in the defects.…”

Managing Peri-Implantitis and Peri-Mucositis with Direct Medication Delivery

“…However, evidence suggests these methods may not be sufficient and results may be similar to conventional debridement 38,39,40,41 Comparing results of open flap debridement of peri-implantitis with and without adjunctive systemic antibiotics demonstrated there was no significant difference in benefits with using the antibiotics 42 The criteria for success in this study was also pocket probing depths of < 5mm which provides an environment where facultative and obligate anaerobes may become the predominant species 43,44 .…”