Open-Heart Surgery without the Need for Donor-Blood Priming in the Pump Oxygenator

Neptune, Wilford B.; Bougas, James A.; Panico, Frederick G.

doi:10.1056/nejm196007212630302

Cited by 63 publications

(15 citation statements)

References 3 publications

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“…12 The original technique was essentially modified by Rosengart in the 1990s. 6 Over the course of history, the technique, as well as the primary question, was modified in a series of studies.…”

Section: Discussionmentioning

confidence: 99%

Pre-filling of the extracorporeal circuit with autologous blood is safe, but not effective in optimizing biocompatibility in high-risk patients

et al. 2012

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Section: Discussionmentioning

confidence: 99%

Pre-filling of the extracorporeal circuit with autologous blood is safe, but not effective in optimizing biocompatibility in high-risk patients

et al. 2012

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“…Hemodilution has been widely applied for hypothermic cardiopulmonary bypass (CPB) for many years. It was first introduced to decrease homologous blood use [26], thereby avoiding the ''homologous blood syndrome'' [18]. Later the effects of hemodilution in counteracting the deleterious rheological consequences of deep hypothermia, such as increased viscosity and red cell rigidity, came to be considered important in minimizing brain injury associated with deep hypothermic circulatory arrest [7].…”

Section: Optimal Hematocrit During Cardiopulmonary Bypassmentioning

confidence: 99%

Neurological Protection During Cardiopulmonary Bypass/Deep Hypothermia

Jonas

1998

Pediatr Cardiol

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“…Sowohl experimentell als auch klinisch wurden bisher durchweg Plasmaex pander, Glukose oder Elektrolytlösungen zur Hämodilution verwandt. (1,2,3,5,6,8,9,14,15) Wichtigste Parameter einer ausgeglichenen Stoffwechsellage während der Perfusion und im postoperativen Verlauf sind die Serum elektrolytkonzentrationen sowie die Werte des Säure-Basen-Haushaltes.…”

Section: Diskussionunclassified

Veränderungen des Elektrolyt- und Säure-Basen-Haushaltes bei Operationen mit kardio-pulmonalem Bypass unter Hämodilution*

Regensburger¹,

Paschen²,

Fuchs³

1972

Thorac cardiovasc Surg

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ZusammenfassungDie Eigenblutverdünnungsperfusion bei der Korrektur angeborener oder erworbener Herzvitien erfordert zur Füllung der Herz-Lungen-Maschine Lösungen, die während der Perfusion nur geringe Stoffwechselveränderungen bewirken. Wir verwenden hierzu seit längerer Zeit Ringer-Laktat-Lösung mit 5 % Glukose. Bisher wurden 10 Patienten mit dieser Perfusionsart operiert. Sie erhielten bis zur Entlassung kein Fremdblut. Als einige der wichtigsten Parameter einer ausgeglichenen Stoffwechsellage während der Operation Changes in the electrolyte and acid-base balance in operations with cardiopulmonary bypass and haemodilution.When haemodilution is used in the correction of congenital and aquired cardiac malformations, it is essential that the heart-lung machine is filled with solutions that only undergo minimal metabolic changes during perfusion. For this purpose, we have used Ringer-lactate solution with 5 °/o glucose for some time. Ten patients have been operated with this type of perfusion and none of them recieved a homologous blood transfusion * Mit Unterstützung der Deutschen Forschungsgemeinschaft im Rahmen des SFB 89 -Kardiologie Göttingen.

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Open-Heart Surgery without the Need for Donor-Blood Priming in the Pump Oxygenator

Cited by 63 publications

References 3 publications

Pre-filling of the extracorporeal circuit with autologous blood is safe, but not effective in optimizing biocompatibility in high-risk patients

Pre-filling of the extracorporeal circuit with autologous blood is safe, but not effective in optimizing biocompatibility in high-risk patients

Neurological Protection During Cardiopulmonary Bypass/Deep Hypothermia

Veränderungen des Elektrolyt- und Säure-Basen-Haushaltes bei Operationen mit kardio-pulmonalem Bypass unter Hämodilution*

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