Smart materials, especially environmentally responsive materials are the basis of many applications, and have attracted much more attentions. In recent years, application research of smart materials in the oil and gas industry has begun. Through principle/performance analysis, application environment comparison, and demand analysis, the application potential and application advantages of self-healing concrete, vibration energy-generating rubber and 4D intelligent structural materials in the downhole operations were evaluated. The application status of smart materials in petroleum engineering is introduced. At the same time, combined with the actual domestic engineering requirements, the long-term effect of improving underground plugging, the shale inhibition of drilling fluid, the downhole control and the efficiency of drilling operations are all proposed. For the application prospects, it is recommended to keep track of the research progress of environmentally responsive materials and carry out pre-research work on the application of advanced smart materials in the field of downhole operations.