In the last decades, significant efforts have been made in urban construction to achieve rapid economic development. However, with climate change on the agenda, there is a growing recognition of the importance of urban sustainable development and of its potential impacts on residents. Reflection reveals that many policies, measures, and tools are inadequate; therefore, public open spaces are regarded as a potential target of urban regeneration strategies. This study explores users’ perceptions of public open spaces through participatory methods. The developed methodology is applied to specific areas of Lhasa, the major city of the Tibet region, which was selected as a test-bed site. The survey involved a selected pool of participants and emphasized the coverage of different types of public open spaces. Investigate factors including personal background, overall satisfaction, user evaluation, usage preference, and willingness to change, analyze key factors based on quantitative survey results. Subsequently, identify the key regenerative design elements that require highlighting. The findings indicate that comfort and safety are emphasized by users of all types of public open spaces. Additionally, their initial impression upon entering a space significantly influences their overall satisfaction with it. Besides, although individual background differences play a role, they are not sufficient to significantly influence the user’s evaluation of the space. However, variations in the purpose of space use result in differences in user evaluations and needs, impacting their attitudes based on the type of space. Finally, urban regeneration design strategies are proposed for various types of public open spaces and users.