The sliding bearing is an important component in machines. The characteristics of the oil film fluid of the sliding bearing is the key factor affecting lubrication, which will affect the wear and reliability of the sliding bearing. Herein, the lubricating oil of the sliding bearing is studied, the oil film flow model considering the cavitation effect is established, the pressure and temperature distribution of the oil film under different rotational speeds is explored, and its influence on oil film pressure and temperature are analyzed. Furthermore, wear tests are carried out to measure the wear amount of the bearing bush under different rotational speeds, and the influence of the fluid characteristics of the lubricating oil film on bearing wear is explored. The simulation and experimental study in this paper can provide a reference for the design of sliding bearings.