Operative Results of Mitral Valve Repair and Replacement in Chronic Ischaemic Mitral Valve Regurgitation

Gimpel, Damian; Cheung, Michael; Bassin, Levi; Jennings, Scott; Weiss, Beatrix; Akhunji, Zakir; Grant, Peter; Wolfenden, Hugh

doi:10.1016/j.hlc.2020.03.007

Cited by 4 publications

(1 citation statement)

References 27 publications

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“…Dilatation of the annulus is the key mechanism of functional regurgitation [9]. Coronary artery disease that causes ischemic changes of the mitral papillary muscles can cause ischemic mitral regurgitation [10].…”

Section: Introductionmentioning

confidence: 99%

Surgical treatment for valvular heart disease: a single centre experience from Sri Lanka

Harischandra¹,

Samson-Himmelstjerna²,

Kannagoda³

et al. 2020

Sri Lanka j Surg

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Section: Introductionmentioning

confidence: 99%

Surgical treatment for valvular heart disease: a single centre experience from Sri Lanka

Harischandra¹,

Samson-Himmelstjerna²,

Kannagoda³

et al. 2020

Sri Lanka j Surg

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Long-term outcomes comparison of mitral valve repair or replacement for secondary mitral valve regurgitation. An updated systematic review and reconstructed time-to-event study-level meta-analysis

Formica,

Gallingani,

Tuttolomondo

et al. 2024

Current Problems in Cardiology

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Comparison of Various Surgical Approaches for Moderate-to-Severe Ischemic Mitral Regurgitation: A Systematic Review and Network Meta-Analysis

Wei,

Dong,

et al. 2024

Rev. Cardiovasc. Med.

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Background: This study aims to systematically review the efficacy of various surgical approaches in the treatment of ischemic mitral regurgitation (IMR). Methods: A comprehensive literature search was conducted using computerized databases, including PubMed, Cochrane Library, Embase, and Web of Science, up to February 2024. In our network meta-analysis, we utilized the Cochrane Handbook tool for quality evaluation, while a consistency model and the odds ratio (OR) were used to compile and analyze the data from the studies included, employing Stata 17.0 software for this purpose. Results: The systematic review included a total of 20 randomized controlled trials (RCTs), which collectively involved 3111 patients and evaluated six different surgical techniques. The network meta-analysis demonstrated that mitral valve repair (MVr) exhibited a significant reduction in 30-day all-cause mortality rates when compared to coronary artery bypass grafting (CABG), mitral valve replacement (MVR), CABG combined with MVR, and transcatheter mitral valve edge-to-edge repair (TEER) using MitraClip. Furthermore, probability ranking analysis suggested that MVr may be the most effective approach in reducing 30-day all-cause mortality, while CABG combined with MVr had significantly fewer renal complications compared to CABG combined with MVR. Probability rankings also indicated that CABG+MVr may be the most effective technique in minimizing renal complications. However, there were no statistically significant differences observed in other outcome measures among the different surgical techniques. Conclusions: Current limited evidence indicates that CABG combined with MVr may be the best surgical approach for patients with IMR. However, these conclusions are tentative and require further confirmation from more additional high-quality studies. INPLASY Registration Number: INPLASY202420049. This study can be accessed at the following detailed address: https://inplasy.com/inplasy-2024-2-0049/, last accessed on February 11, 2024.

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Operative Results of Mitral Valve Repair and Replacement in Chronic Ischaemic Mitral Valve Regurgitation

Cited by 4 publications

References 27 publications

Surgical treatment for valvular heart disease: a single centre experience from Sri Lanka

Surgical treatment for valvular heart disease: a single centre experience from Sri Lanka

Long-term outcomes comparison of mitral valve repair or replacement for secondary mitral valve regurgitation. An updated systematic review and reconstructed time-to-event study-level meta-analysis

Comparison of Various Surgical Approaches for Moderate-to-Severe Ischemic Mitral Regurgitation: A Systematic Review and Network Meta-Analysis

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