Ophthalmic Artery Microembolism in Giant Cell Arteritis

Schäuble, Barbara; Wijman, Christine A.C.; Koleini, Behrooz; Babikian, Viken L.

doi:10.1097/00041327-200012000-00015

Cited by 4 publications

(3 citation statements)

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“…Giant cell arteritis may rarely present with CNS involvement . An interesting case study detected MES in the ophthalmic, anterior, and middle cerebral arteries in patients with giant cell arteritis . A case of a 73‐year‐old man with unremarkable headache history presenting with multiple acute infarctions located predominantly in posterior circulation is presented in Figure .…”

Section: Vasculitismentioning

confidence: 99%

“…158 An interesting case study detected MES in the ophthalmic, anterior, and middle cerebral arteries in patients with giant cell arteritis. 159 A case of a 73-year-old man with unremarkable headache history presenting with multiple acute infarctions located predominantly in posterior circulation is presented in Figure 5. Cervical ultrasound and digital subtraction angiography identified bilateral vertebral (extracranial segment), left supraclinoid internal carotid artery, and bilateral superficial temporary artery involvement indicative of giant cell arteritis that was confirmed with superficial temporal artery biopsy.…”

Section: Vasculitismentioning

confidence: 99%

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The Role of Transcranial Doppler Monitoring in Patients with Multi‐Territory Acute Embolic Strokes: A Review

Kargiotis

Psychogios

Safouris

et al. 2019

Journal of Neuroimaging

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Acute multi‐territory, embolic cerebral infarctions are often associated with serious underlying clinical conditions including the presence of highly “active” emboligenic sources causing that in turn may result in high early recurrence rates. Prompt diagnosis, risk stratification, and treatment are substantial for the prevention of subsequent embolization that would result in further clinical deterioration. Among other clinical investigations, transcranial Doppler (TCD) monitoring is highly efficacious for the detection of microembolic signals (MES) that correspond to microthrombi entering the intracranial circulation. The presence and burden of MES, especially in multiple intracranial arteries, is clearly associated with an increased risk of symptomatic, recurrent embolization, and thus can justify a more aggressive treatment approach (clopidogrel load followed by dual antiplatelet therapy or alternatively therapeutic dose of low‐molecular‐weight heparin). In this narrative review, we discuss the most important causes of multi‐territory embolic ischemic strokes and also underscore the utility of TCD as a noninvasive tool for the diagnosis, risk stratification, and treatment.

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Section: Vasculitismentioning

confidence: 99%

Section: Vasculitismentioning

confidence: 99%

The Role of Transcranial Doppler Monitoring in Patients with Multi‐Territory Acute Embolic Strokes: A Review

Kargiotis

Psychogios

Safouris

et al. 2019

Journal of Neuroimaging

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“…Stroke may occur in GCA and may be due to thrombosis,19 a mixture of intimal hyperplasia and distal thrombosis35 or microembolism 36. Although the vertebral arteries appear to be inflamed in 75–100% of cases of GCA studied at autopsy,19 clinically significant features of vertebrobasilar insufficiency are uncommon in GCA.…”

Section: Gca and Pmr: Two Diseases Or One?mentioning

confidence: 99%

Diagnosis and management of giant cell arteritis and polymyalgia rheumatica: challenges, controversies and practical tips

McDermott

Pease

2013

Postgraduate Medical Journal

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Giant cell arteritis (GCA) and polymyalgia rheumatica (PMR) are inflammatory rheumatic diseases that may present to a variety of disciplines and specialities. The mainstay of treatment is glucocorticoids (steroids); together PMR and GCA now represent one of the most common reasons for medium-to-high dose, long-term glucocorticoid treatment in primary care. However, adverse effects of glucocorticoids are common in these patients. Management of both diseases involves balancing the symptoms and risks of the disease against the adverse effects and risks of glucocorticoids. The crucial first step in management is to make a firm, well-documented diagnosis, since once glucocorticoids are started they can mask the symptoms of a number of other diseases. Diagnosis however can be challenging and there are still substantial gaps in the evidence for treatment.

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Idiopathic Non-atherosclerotic Carotid Artery Disease

Harriott

2019

Curr Treat Options Cardio Med

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Ophthalmic Artery Microembolism in Giant Cell Arteritis

Cited by 4 publications

References 0 publications

The Role of Transcranial Doppler Monitoring in Patients with Multi‐Territory Acute Embolic Strokes: A Review

The Role of Transcranial Doppler Monitoring in Patients with Multi‐Territory Acute Embolic Strokes: A Review

Diagnosis and management of giant cell arteritis and polymyalgia rheumatica: challenges, controversies and practical tips

Idiopathic Non-atherosclerotic Carotid Artery Disease

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