Ophthalmic findings of newly diagnosed leprosy patients in Istanbul Leprosy Hospital, Turkey

Abstract

ABSTRACT. The objective of this study was to detect ocular lesions of newly diagnosed leprosy cases admitted to Istanbul Leprosy Hospital. The patients were categorized according to sex, age, type of leprosy and duration of the disease. Their eyes were categorized as with or without ocular findings due to leprosy. The total number of patients was 21. The mean age was 22∫4.6 years, the duration of the disease was 36.3∫19.6 months. Madarosis was the most common finding in this group. It was found in 15 patients (71.4%, 95% confidence interval (CI) 47.8-88.7%). As a second common finding related to corneal alterations, 13 patients had nerve thickening (61.9%, 95% CI 38.4-81.8%). None of our patients had trichiasis, episcleritis, scleritis, cataract, iris atrophy, iris pearl, abnormal vitreous or retinal findings.

Alterações oculares na hanseníase, observadas em pacientes ambulatoriais do serviço de referência da cidade de Rio Branco, Acre - Brasil

“…O mesmo ocorre na maior parte dos estudos, exceto quando realizados em pacientes de hanseníase recém-diagnosticados (12) . A cegueira causada pela catarata preocupa, porque, apesar de reversível, a acuidade visual após cirurgia pode ser menor nos pacientes de hanseníase do que na população em geral, segundo alguns autores (41) .…”

“…Em conseqüên-cia, a Organização Mundial de Saúde (OMS) estima que o mal de Hansen seja a causa de cegueira em 50.000 a 100.000 pessoas em todo o mundo (8) . Apesar das complicações oculares ocorrerem cerca de 5 a 10 anos após o início da hanseníase (1) , cada vez mais são descritas manifestações oculares em pacientes recém-diagnosticados (9)(10)(11)(12)(13) . Na Amazônia, são escassas as publicações sobre a morbidade ocular na hanseníase (14) , daí o objetivo do presente estudo: descrever as alterações oculares em pessoas afetadas pela hanseníase dentro ou fora de atividade da doença, acompanhadas em serviço ambulatorial de referência da cidade de Rio Branco, Acre, durante seis meses.…”

Madarosis from mitochondriopathy

“…Madarosis is aetiologically heterogeneous, as listed in Table 1. Most frequently madarosis is observed in patients with leprosy, where it has been reported in 27–76% of cases (Hogeweg & Leiker 1983; Soshamma & Surayawanshi 1989; Dana et al 1994; Cakiner & Karacorlu 1998; John & Daniel 1999). Madarosis is also frequently found in patients with malignomas or as paraneoplastic syndrome (Leib et al 1991; Saghari et al 2002; Kodama et al 2004).…”

Visceral leprosy

“…3 Pterygium, corneal scarring, corneal anesthesia, reduced corneal reflexes, lagophthalmos, iridocyclitis, conjunctivitis, ectropion, dry eyes, scleritis, uveitis, keratitis, cataracts, and glaucoma may be present, and could contribute to decreased vision. 182–189 Early, appropriate ocular management may help to reduce the disabling unilateral or bilateral blindness that may occur in a small but significant proportion of patients (3–10%). 188,190–193 …”

“… 182–189 Early, appropriate ocular management may help to reduce the disabling unilateral or bilateral blindness that may occur in a small but significant proportion of patients (3–10%). 188,190–193 …”