Ophthalmo-Neurological Symptoms in Malignant Nasopharyngeal Tumours.[Summary]

Malignant Disease of the Nasopharynx

“…Since the cell type is not distinct it is probably a form of anaplastic carcinoma and has been classified among the carcinomata. This is in agreement with Teoh's (1957 and1967) view that almost all malignant neoplasia of the nasopharynx are carcinomata, and as he so well demonstrates, all varieties of histopathological picture may be demonstrated in a single carcinoma. As Willis (1953) says "the controversy is largely over names; these denote, not distinct entities, but only variants of the entity epidermoid carcinoma of the pharynx".…”

“…Gooddy (1953) stressed the infrequency of one's personal experience, for he was only able to find 7 verified cases among 35,000 patients attending the National Hospital, Queen Square, during a 4-year period. Godtfredsen (1947) collected 454 cases from four Scandinavian Radiological Clinics during a 10-year period.…”

“…Capps (1965) elected to classify them as sarcomas. However, Digby (1951), and Teoh (1957and 1967, whose experiences are immense, stressed the entire absence of lymphoid tissue in metastases that occurred in sites other than lymphoid tissue and suggest that they are largely carcinomata. This finding confirms our view that the lymphoid element in a "lymphoepithelioma" is merely an associated tissue response and not an essential element oi the tumour.…”

“…The wall of the nasopharynx is composed of three coats: (i) The innermost lining of pseudo-stratified ciliated columnar epithelium down to the level of eustachian tube; stratified squamous epithelium elsewhere; and stratified columnar at transitional areas (Hollender, 1946;Teoh, 1957).…”

Distant metastases of nasopharyngeal carcinoma: A study of 256 male patients

“…This is in contrast to Teoh's data [22,23] in whose series bones were routinely sectioned at autopsy. It is not clear whether bones were routinely sectioned in Godtfredsen's [24] series.…”