Ophthalmologic Changes Produced by Pituitary Tumors*

Chamlin, Max; Davidoff, Leo M.; Feiring, Emanuel H.

doi:10.1016/0002-9394(55)91869-9

Cited by 49 publications

(21 citation statements)

References 9 publications

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“…The more frequent non-paretic type of diplopia, first reported by Beckmann and Kubie (1929) and more recently by Chamlin, Davidoff, and Feiring (1955), seems to be less well recognized. Epilepsy occurs under circumstances similar to cranial nerve lesions, and its frequency pre-operatively in the present series (2-3 per cent.)…”

Section: Discussionmentioning

confidence: 97%

Pituitary adenoma. Preoperative symptomatology in a series of 260 patients.

Elkington¹

1968

British Journal of Ophthalmology

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STUDY of the syndromes associated with pituitary adenoma began with the description of acromegaly by Marie (1886), and many reports of the symptomatology of the tumour have since appeared (Cushing, 1912;Cairns, 1935;Henderson, 1939;Jefferson, 1940;Bakay, 1950;Younghusband, Horrax, Hurxthal, Hare, and Poppen, 1952;Nurnberger and Korey, 1953; Mogensen, 1957;Ray and Patterson, 1962;Poppen, 1963). Recently a series of 260 patients with pituitary adenoma selected for combined surgery and radiotherapy because of failing vision has been studied. Both the effect of treatment on vision (Elkington and McKissock, 1967) and the subsequent endocrine function (Elkington, Buckell, Monamy, and Jenkins, 1967) have been described elsewhere. The present communication reports the pre-operative symptomatology in these patients and suggests how early diagnosis of pituitary adenoma, necessary if the best results are to be obtained from treatment, may be made on clinical grounds. Material and MethodsThe case records of 260 patients were examined. They had been operated on by one surgeon at either the National Hospital for Nervous Diseases, Queen Square, or Atkinson Morley's Hospital, Wimbledon, between 1938 and. The nature of the tumour had been confirmed by histological examination in 246; in fourteen the clinical and operative findings alone were accepted as diagnostic. Failing vision was the sole indication for operation in almost every instance, and detailed records of both the visual acuity and the visual fields were available. The former was expressed by Snellen or Jaeger reading type, and the latter was shown in charts of visual field obtained by perimetry. Quantitation of visual function using the method described by Colby and Kearns (1962) was not attempted, a simple descriptive classification being used for the visual fields. Evidence of endocrine function was not consistently recorded, and investigation of endocrine function was infrequent. FindingsOf the total of 260 patients, 145 were males and 115 females. The youngest patient was aged 14 years and the oldest 72 years at the time of operation. The greatest incidence of symptoms necessitating treatment occurred in the fifth decade in both sexes. Details of age, sex, and tumour type are given in Tables I and II (opposite).

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Section: Discussionmentioning

confidence: 97%

Pituitary adenoma. Preoperative symptomatology in a series of 260 patients.

Elkington¹

1968

British Journal of Ophthalmology

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“…1 Hemifield slide phenomenon has been most commonly associated with bitemporal hemianopia, usually secondary to chiasmal compression by a pituitary adenoma. 5,6,11,12 Elkington described the preoperative symptomatology of patients with pituitary adenoma, and was the first to attribute the symptom to his patients' inability to correctly register an image in each eye. 13 In his series, 170 of 260 patients had bitemporal visual field loss and 84 of those (49%) complained of diplopia without having ocular palsy.…”

Section: Discussionmentioning

confidence: 99%

Hemifield Slide Phenomenon as a Result of Heteronymous Hemianopia

Peragallo¹,

Bialer²,

Pineles³

et al. 2014

Neuro-Ophthalmology

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“…Compression of the optic nerve, the chiasm or the optic tract by tumors may lead to visual loss [3,5,9]. One typical situation is the bitemporal visual field defect in cases of pituitary tumors compressing the chiasm.…”

Section: Introductionmentioning

confidence: 99%