Ophthalmological significance of HLA associated uveitis

Feltkamp, T. E. W.

doi:10.1038/eye.1990.133

Cited by 42 publications

(11 citation statements)

References 9 publications

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“…This is the highest association of any HLA antigen with a human disease [97]. Testing for HLA-A29 in useful in making the diagnosis as it has a sensitivity of 96% and specificity of 93% [48, 99]. …”

Section: Main Textmentioning

confidence: 99%

Multi-modal imaging and anatomic classification of the white dot syndromes

et al. 2017

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The white dot syndromes (WDS) are a diverse group of posterior uveitidies that share similar clinical findings but are unique from one another. Multimodal imaging has allowed us to better understand the morphology, the activity and age of lesions, and whether there is CNV associated with these different ocular pathologies. The “white dot syndromes” and their uveitic masqueraders can now be anatomically categorized based on lesion localization. The categories include local uveitic syndromes with choroidal pathology, systemic uveitic syndromes with choroidal pathology, and multifocal choroiditis with outer retinal/choriocapillaris pathology with uveitis and without uveitis. Neoplastic and infectious etiologies are also discussed given their ability to masquerade as WDS.

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Section: Main Textmentioning

confidence: 99%

Multi-modal imaging and anatomic classification of the white dot syndromes

et al. 2017

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“…HLA-A29 typing has an estimated sensitivity of 96% and specificity of 93% 43. Typically, other laboratory studies are normal, but can be valuable in ruling out other conditions in the differential diagnosis.…”

Section: Diagnosismentioning

confidence: 99%

Birdshot retinochoroidopathy

Gasch

Smith

Whitcup

1999

British Journal of Ophthalmology

111

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“…However, in other patients the chronicity of the disease in the absence of systemic features of sarcoidosis makes this unlikely. All patients with clinical features of birdshot chorioretinopathy underwent testing for HLA‐A29, which has been shown to be 96% sensitive and 93% specific for birdshot 9 . When combined also with the clinical appearances, it seems unlikely that any cases of birdshot were included in this study group.…”

Section: Discussionmentioning

confidence: 99%